Results 171 to 180 of about 838,035 (305)
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Acceptability of a social prescribing program (REDE D+) for self-care and health literacy among people with type 2 diabetes mellitus-a qualitative study. [PDF]
Oliveira D +3 more
europepmc +1 more source
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
ABSTRACT: This space presents/displays the opportunity to develop a interdisciplinary proposal and to as well assume the leadership in the impulse of proposals that explore the use of methodologies of vanguard for the analysis of the social reality.
openaire +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Redes Sociales Protocooperativas
Este trabajo hace uso de la interdisciplinariedad con la biolog?a, para construir un concepto que explica la configuraci?n actual de la Web 2.0, su expansi?n y el crecimiento. Para ilustrar el proceso he utilizado la analog?a con las relaciones ecol?gicas que se pueden establecer sobre la base de las interacciones entre las especies neutras, positivas ...
openaire +1 more source
ResearchGate as a strategic tool to enhance the scientific visibility in Speech-Language Pathology and Audiology. [PDF]
Fidêncio VLD.
europepmc +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source

