Results 81 to 90 of about 8,345 (259)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Social support network and quality of life in multiple sclerosis patients
Arquivos de Neuro-PsiquiatriaObjective To analyse the relationship between the social support network (SSN) and health related quality of life (HRQOL) in multiple sclerosis (MS) patients. Methods The sample comprised 150 consecutive MS patients attending our MS clinic.
David Castro Costa +2 more
doaj +1 more source
Características estruturais das redes sociais significativas de mães em unidade neonatal [PDF]
Psicologia USPResumo: As internações neonatais foram fortemente impactadas pela pandemia de covid-19, especialmente as redes sociais de apoio, reconhecidas por sua relevância protetiva, sofreram alterações significativas.
Camila Marchiori Pereira +2 more
doaj +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
, 2015 Novedosos estudios muestran cómo a través de técnicas combinadas de análisis de redes y de minería de datos (especialmente en Twitter, que ofrece datos abiertos) es posible identificar climas de opinión dentro de colectivos de individuos inmersos en procesos históricos ...
openaire +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Facebook: rede social educativa?
, 2010 Actualmente, as redes sociais fazem parte da vida dos nossos alunos. O Facebook é, provavelmente, o principal sítio de encontro, comunicação, partilha e interacção de ideias e assuntos de interesse comum, entre os estudantes universitários. Neste contexto e dadas as possibilidades que as redes sociais oferecem para a criação de um ambiente de ...
Patrício, Maria Raquel +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Revista Brasileira de Geriatria e GerontologiaOBJETIVOS: Descrever o perfil sociodemográfico e a rede social dos idosos residentes na comunidade de Ermelino Matarazzo, por meio de inquérito epidemiológico.
Marisa Accioly Domingues +5 more
doaj +1 more source