Results 41 to 50 of about 233,572 (268)

Spectral redemption: clustering sparse networks [PDF]

open access: yes, 2013
Spectral algorithms are classic approaches to clustering and community detection in networks. However, for sparse networks the standard versions of these algorithms are suboptimal, in some cases completely failing to detect communities even when other ...
Krzakala, Florent   +6 more
core   +3 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

La visión femenina de una vida auténtica en la novela El velo pintado de W. Somerset Maugham

open access: yesChurch, Communication and Culture, 2019
A poem by Shelley gives the title to William Somerset Maugham’s novel The Painted Veil, published in 1925. The moral of the poem is very pessimistic: the veil of life should not be lifted, because underneath there is no truth.
Antonio Malo
doaj   +1 more source

O fetiche do eu autônomo: consumo responsável, excesso e redenção como mercadoria The fetish of the autonomous self: responsible consumption, excess and redemption as a commodity

open access: yesPsicologia & Sociedade, 2010
Embora esteja no centro do projeto moderno, a ideologia de um eu autônomo ganha contornos novos a partir da segunda metade do século XX, quando começa a se delinear a sociedade "sem limites".
Isleide Arruda Fontenelle
doaj   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi   +8 more
wiley   +1 more source

Dwa źródła usprawiedliwienia

open access: yesPaedagogia Christiana, 2015
Artykuł dotyczy jednej z kluczowych doktryn chrześcijaństwa – usprawiedliwienia, która w okresie nowożytnym stało się teologicznym powodem podziału Kościoła na Zachodzie.
Piotr Kostyło
doaj   +1 more source

Dostoevsky overcomes Nihilism: Luigi Pareyson reads The Brothers Karamazov

open access: yesWrocławski Przegląd Teologiczny, 2021
“Dostoevsky’s novels are pure philosophy,” declared Luigi Pareyson (1918–1991), an Italian existentialist. He presents a Christian Dostoevsky capable of overcoming the nihilistic onslaught of a post-Christian culture, both in its harshest and “weaker ...
Pablo Blanco-Sarto
doaj   +1 more source

Menorah Review (No. 7, Spring, 1986) [PDF]

open access: yes, 1986
Incomplete Redemption -- Alternatives for a New Jewish-Christian Future -- Books Received -- Identifying Jewish Art: A Question of Moral Consciousness?

core   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

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