Results 231 to 240 of about 1,684,510 (297)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae from human carriage, the human-polluted environment, and food: Molecular epidemiology of two prospective cohorts in five European metropolitan areas. [PDF]

PLoS One
Verschuuren TD, Guther J, Riccio ME, Martak D, Salamanca E, Göpel S, Conzelmann N, Scharringa J, Musicha P, Autenrieth IB, Cooper BS, Hocquet D, Tacconelli E, Rodríguez-Baño J, Harbarth S, Fluit AC, Peter S, Kluytmans JAJW.   +17 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

[Social determinants of therapeutic adherence among users of the primary health care system's cardiovascular health program in ChileDeterminantes sociais da adesão terapêutica entre usuários do programa de saúde cardiovascular na atenção primária à saúde do Chile]. [PDF]

Rev Panam Salud Publica
Herrera Atton D, Olivi A, Reyes Cabrera P, García Ubillo V, Veloz Baeza A, Veintimilla Carrión KS, Sánchez Lagos S.   +6 more
europepmc   +1 more source

Coping, stress, and burden among caregivers of older adults with Alzheimer's: a network analysis. [PDF]

Dement Neuropsychol
Marques IVP, Lin CC, da Silva EQ, Tavares BFS, da Silva TC, do Nascimento JRA, de Oliveira DV.   +6 more
europepmc   +1 more source

Factors associated with common mental disorders, suicidal risk, and stimulant use in college students. [PDF]

Rev Bras Enferm
Bianchi GC, Miasso AI.
europepmc   +1 more source

[Contemporary challenges for digital health: literacy, media education, and prevention of disinformationDesafíos actuales para la salud digital: alfabetización, educación mediática y prevención de la desinformación]. [PDF]

Rev Panam Salud Publica
Mendonça AVM, de Sousa MF.
europepmc   +1 more source