Results 161 to 170 of about 58,820,429 (260)

Heat Stress Promotes Fibroblast‐Derived WNT5A Secretion Through m6A Modification to Activate Melanogenesis

Advanced Science, EarlyView.
Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan, Yaqing Wen, Yushan Zhang, Lan Zhang, Jianjian Zhu, Zhen Tang, Ling Jiang, Chuhan Fu, Shu Zhou, Keyi Zhang, Jiangfeng Huang, Li Lei, Jing Chen, Qinghai Zeng   +13 more
wiley   +1 more source

Characterization and quantification of microplastics in marine sediments of the Colombian Caribbean. [PDF]

PeerJ
Garzón-Rodríguez L, Tigreros-Benavides P, Ochoa-Mogollón J, Herrera-Villarraga G, Sarmiento-Sánchez C, Polania-Zenner P, Rozo-Torres G, Sanjuan-Muñoz A, Franco-Herrera A.   +8 more
europepmc   +1 more source

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

Advanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang, Qiubo Chen, Shihai Lan, Liang Zhu, Shuaiyu Liu, Yan Xia, Yalu Zhang, Hanhui Yao, Yongman Liu, Shangquan Wu, Qingchuan Zhang   +10 more
wiley   +1 more source

Reunión del Comité de Redes del día 31 de enero 2019

, 2019
Agenda del Día: 1. Consulta Servicios de TIC, para Red Nicté.- Lourdes Velázquez (UNAM). 2. Avances del Plan Anual CUDI, Instancia Operadora de la Red Nacional para la Investigación Científica, Tecnológica y la Educación (Red Nicté).- Lourdes Velázquez ...
Miembros del Comité de Redes
core  

Microbiological quality and antimicrobial resistance of Pseudomonas aeruginosa in drinking water systems of the old terminal of Jorge Chávez International Airport: potential role as environmental reservoir. [PDF]

Rev Peru Med Exp Salud Publica
Sulca-Galarza LE, Robles-Camarena RC, Sánchez-Rojas TL, Rodríguez-Gonzales AF.   +3 more
europepmc   +1 more source

Surgical Induction of Endometriosis in Female Mice. [PDF]

Bio Protoc, 2020
Escudero-Lara A, Cabañero D, Maldonado R.   +2 more
europepmc   +1 more source

Consequences of Viral Infection and Cytokine Production During Pregnancy on Brain Development in Offspring. [PDF]

Front Immunol, 2022
Elgueta D, Murgas P, Riquelme E, Yang G, Cancino GI.   +4 more
europepmc   +1 more source

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

Advanced Science, EarlyView.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin, Shaojie Dong, Yue Jia, Zhao Xu, Peiqi Liu, Zhaojing Ding, Yuxin Liao, Rui Zou, Jinsong Hu, Bo Cheng, Lin Niu   +10 more
wiley   +1 more source

Reunión del Comité de Redes del día 28 de marzo 2019

, 2019
Agenda del Día: 1. Consulta Servicios de TIC, para Red Nicté.- Lourdes Velázquez (UNAM). 2. Avances del Plan Anual CUDI, Instancia Operadora de la Red Nacional para la Investigación Científica, Tecnológica y la Educación (Red Nicté).- Lourdes Velázquez ...
Miembros del Comité de Redes
core  

[The presence of Ptolemy's Geography in Portuguese libraries: inventory, contextualisation and uses of an ancient scientific book]. [PDF]

Hist Cienc Saude Manguinhos
Maguelniski D, Bauab FP, Oliveira FR.
europepmc   +1 more source