Results 21 to 30 of about 410 (242)

Um Mecanismo de Offloading para Redes de Sensores Veiculares

Anais do XXXVII Simpósio Brasileiro de Redes de Computadores e Sistemas Distribuídos (SBRC 2019), 2019
A rede veicular refere-se a uma promissora abordagem de ter veículos equipados com dispositivos de comunicação sem fio capazes de estabelecer comunicação com outros veículos. Cada veículo é capaz de recolher, processar e divulgar informações sobre si e seu ambiente.
Douglas Leite Leal Moura, André Luiz Lins de Aquino, Antonio Alfredo Ferreira Loureiro   +2 more
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Prospectiva de seguridad de las redes de sensores inalámbricos

Revista UIS Ingenierías, 2021
In Wireless Sensor Networks (WSN), nodes are vulnerable to security attacks because they are installed in a harsh environment with limited power and memory, low processing power, and medium broadcast transmission.Therefore, identifying threats, challenges, and solutions of security and privacy is a talkingtopic today. This article analyzes the research
Fernando Gutiérrez-Portela, Florina Almenares-Mendoza, Liliana Calderón-Benavides, Efren Romero-Riaño   +3 more
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Avaliação da usabilidade das redes de sensores subaquáticas através de documentos patentários

Vetor, 2013
As redes de sensores subaquáticas são fundamentais para coleta de dados oceanográficos, tendo diversas aplicações, por exemplo, predições sísmicas, exploração offshore de petróleo e gás, controle da qualidade da água e estudos das interações entre ...
Maria Elisa Marciano Martinez, Arthur Aprígio de Melo, Patrícia Carvalho dos Reis   +2 more
doaj   +4 more sources

Diseño y Creación de Sensor Inalámbrico y Registrador para Plataforma de Prueba de Redes de Sensores Inalámbricos con Tecnología Zigbee Utilizando Módulos XBEE

Tecnología y Ciencia, 2018
Gracias al avance en las tecnologías de comunicaciones inalámbricas y al uso de las redes de sensores inalámbricos se ha facilitado la transmisión de datos de sensores ambientales.
Pablo S. Gaspoz, Emanuel Baer
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Plataformas tecnológicas aplicadas al monitoreo climático

Prospectiva, 2014
Este artículo muestra la importancia que han tomado las tecnologías embebidas de bajo costo para aplicaciones de monitoreo ambiental, usadas en redes de sensores inalámbricos, destacándose una de ellas.
Gabriel Piñeres Espitia
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source