Results 251 to 260 of about 3,629,594 (294)

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

Advanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang, Meng‐Meng Liu, Yu‐Chen Zhao, Jia‐Yi Li, Wen Li, Xin Yu   +5 more
wiley   +1 more source

Relationship between health-seeking behavior and digital health literacy in epilepsy patients. [PDF]

Rev Esc Enferm USP
Serin EK, Tülüce D, Usta S.
europepmc   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source

[Fragmentation, heterogeneity, and challenges facing the Argentine healthcare system in the context of emerging ultraliberal reforms]. [PDF]

Cad Saude Publica
Martich E, Pereira AMM, Cesse EÂP.
europepmc   +1 more source

Self‐Sustaining Hybrid Passive Cooler Enabling Highly Effective Thermal Management for Outdoor Electronics

Advanced Science, EarlyView.
An innovative hybrid passive cooler integrates a porous radiative coating and an atmospheric moisture‐harvesting hydrogel within a melamine sponge skeleton, synergizing radiative cooling, sensible‐heat absorption, and latent‐heat evaporation. It maintains an average 8.3°C sub‐ambient cooling under sunlight and a maximum ∼42.4°C drop under 2000 W·m−2 ...
Qingyuan Du, Meng Yang, Maoning Li, Guangzhe Chen, Yunpeng Hu, Dandan Li, Dazhi Sun   +6 more
wiley   +1 more source

Strategies for tackling fake news in healthcare: a complex approach from a nursing perspective. [PDF]

Rev Esc Enferm USP
Costa LDS, Ventura CAA, Marcon SS, Duarte SDCM, Silva TPD, Nogueira ALA, Silva ÍR.   +6 more
europepmc   +1 more source

An Interpretable, Data‐Driven, Hierarchical Multi‐Domain Fusion Framework for Classification and Motor Function Scoring in Chronic Ankle Instability

Advanced Science, EarlyView.
An AI‐enabled digital twin framework integrates wearable EMG sensing with hierarchical multi‐domain fusion to classify chronic ankle instability, distinguish clinically relevant subtypes, and generate continuous motor function scores. Clinically interpretable functional stratification and SHAP‐based biomarker analysis provide transparent decision ...
Tianle Jie, Datao Xu, Zhifeng Zhou, Bas Van Hooren, Huiyu Zhou, Yi Yuan, Xiangli Gao, Monèm Jemni, Liangliang Xiang, Meizi Wang, Justin Fernandez, Tibor J. Goda, Yaodong Gu   +12 more
wiley   +1 more source

Health promotion strategies for adolescents with suicidal behavior: a scoping review. [PDF]

Rev Esc Enferm USP
Bezerra EADAC, Heidemann ITSB, Souza AA, Fonseca ERD, Coelho CT, Daza PMO, Beckert RAT, Ferreira AA.   +7 more
europepmc   +1 more source

[Knowledge of first aid for epileptic seizures among the general population and relatives of patients with epilepsy]. [PDF]

An Sist Sanit Navar
Viloria-Alebesque A, Bono-Velilla Á, Bellosta-Diago E, Navarro-Pérez MP, Reyes-Perera N, Santos-Lasaosa S.   +5 more
europepmc   +1 more source