Results 61 to 70 of about 88,030 (340)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Asteroid detumbling for redirection missions
, 2018 In order to accomplish most asteroid redirection missions, rotational control of the asteroid body is required. Small near-Earth asteroids tend to exhibit a significant range of rotational and tumbling properties.
Bazzocchi, Michael C. F.,, Emami, Reza,
core +1 more source
A Fast Connection-Time Redirection Mechanism for Internet Application Scalability [PDF]
, 2001 Applications that are distributed, fault tolerant, or perform dynamic load balancing rely on redirection techniques, such as network address translation (NAT), DNS request routing, or middleware to handle Internet scale loads.
Earl Barr +8 more
core +1 more source
MI Bridge and ReDirection Clinical Trials
, 2023 This repository contains registration materials for RCTs assessing the MI Bridge and ReDirection ...
Timothy J. Luke +2 more
core +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Taxes, subsidies and unemployment - a unified optimization approach
Croatian Operational Research Review, 2010 Like a linear programming (LP) problem, linear-fractional programming (LFP) problem can be usefully applied in a wide range of real-world applications. In the last few decades a lot of research papers and monographs were published throughout the world ...
Erik Bajalinov
doaj
A Large-Scale Investigation of URLs Abusing Translation Proxies
IEEE AccessPhishing attackers increasingly abuse reputable third-party infrastructure to reduce user suspicion and weaken reputation-based defenses. This strategy becomes particularly effective in multi-stage redirection chains that traverse trusted proxy services.
Doyeon Kim, Yaeji Song, Jeman Park
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Strategic Redirection (Corporate Restructuring Strategy).
, 1985 This study researched the phenomenon of strategic change at the corporate level among large manufacturing firms. Shifts in strategic direction were measured using changes in the importance of the firm's dominant business activity or core business.
Wiersema, Margarethe Frieda
core +1 more source