Results 61 to 70 of about 193,265 (264)
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Feminist Politics in the Age of Recognition: A Two-Dimensional Approach to Gender Justice
In the course of the last thirty years, feminist theories of gender have shifted from quasi-Marxist, labor-centered conceptions to putatively “post-Marxist”culture- and identity-based conceptions.
Nancy Fraser
doaj +2 more sources
Indonesia’s 120.5-million-hectare forest area shrinks due to deforestation, mainly community cultivation. Forest Land Redistribution (FLR) via programs like Social Forestry, TORA, KHDPK, Food Estate, and infrastructure development attempts to address ...
Hendra Gunawan +22 more
doaj +1 more source
Status and Development: How Social Hierarchy Undermines Well-Being
Although social status has been shown to be a fundamental motive for individuals, theories of development have largely overlooked the role of status in shaping economic and social outcomes.
Poulomi Chakrabarti
doaj +1 more source
How economic success shapes redistribution: The role of self-serving beliefs, in-group bias and justice principles [PDF]
In the face of economic inequalities, redistribution of wealth is a key debate for society, and understanding the reasons why individuals may support more or less redistribution can inform this debate.
Camille Dorin +4 more
doaj
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Trends in Personal Income Tax Progression in OECD Countries in the Context of Income Redistribution
In recent years there has been an evident, widespread increase in income disparities in OECD countries. Progressive Personal Income Tax, which enables adjustment of the tax burden to individual’s capacity to pay, is one of the fundamental instruments ...
Małgorzata Mazurek-Chwiejczak
doaj +1 more source
Clinical Validation of Plasma p‐217tau in Neurological Diseases
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source

