Results 91 to 100 of about 19,884,535 (281)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
On enforcing stability for data-driven reduced-order models
International audienceIn this paper, we address stability enforcement for reduced-order models computed from data (transfer function measurements).
Poussot-Vassal, C. +8 more
core +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Obtaining Reduced-Order Stochastic Models
Recent approaches to stochastic model reduction have followed the balancing approach introduced by Moore for the deterministic model reduction problem.
Vaccaro, Richard J., Richard J. Vaccaro
core +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Vortex-induced vibration of catenary riser: reduced-order modeling and lock-in analysis using wake oscillator [PDF]
A new reduced-order model capable of analyzing the vortex-induced vibration of catenary riser in the ocean current has been developed. This semi analytical-numerical approach is versatile and allows for a significant reduction in computational effort for
O'Brien, P. +4 more
core +3 more sources
Reduced‐order modelling of an adaptive mesh ocean model
AbstractA novel proper orthogonal decomposition (POD) model has been developed for use with an advanced unstructured mesh finite‐element ocean model, the Imperial College Ocean Model (ICOM, described in detail below), which includes many recent developments in ocean modelling and numerical analysis.
Fang, F. +6 more
openaire +3 more sources
Structural Control Design on Reduced Order Models
Details on reduced order ...
CASCIATI, FABIO, FARAVELLI, LUCIA
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source

