Results 101 to 110 of about 19,884,535 (281)

Thermospheric Neutral Species Reduced Order Probabilistic Emulator: Dimensionality Reduction

open access: yesSpace Weather
One area of significant interest for space operations is the application of physics‐based thermosphere models for accurate drag modeling. However, their computational complexity limits their use in operational settings.
Nathaniel E. Michek, Piyush M. Mehta
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Towards Universal Non-Dimensional Characterization of the Oscillatory Dynamics of Wind Turbine Rotors of Multiple Sizes

open access: yesDynamics
One concern in the field of Horizontal Axis Wind Turbines (HAWTs) is what control strategies are needed to handle gust pulses in the wind to prevent extreme oscillations of the blades to reduce fatigue stress, prevent blade rupture, and extend the ...
North Yates   +2 more
doaj   +1 more source

Reduction of nonlinear models for control applications

open access: yes, 2013
A systematic approach to the model reduction of high-fidelity fluid-structure-flight models and the subsequent flight control design for very flexible aircraft is considered. The test case is for an unmanned aerial vehicle.
Da Ronch, A.   +4 more
core   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Adaptive tracking for complex systems using reduced-order models [PDF]

open access: yes, 1990
Reduced-order models are considered in the context of parameter adaptive controllers for tracking workspace trajectories. A dual-arm manipulation task is used to illustrate the methodology and provide simulation results.
Carignan, Craig R.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Using the Neumann series expansion for assembling Reduced Order Models

open access: yesApplied and Computational Mechanics, 2014
An efficient method to remove the limitation in selecting the master degrees of freedom in a finite element model by means of a model order reduction is presented.
Nasisi S., Valášek M., Vampola T.
doaj  

Characterizing Wake Behavior of Adaptive Aerodynamic Structures Using Reduced-Order Models

open access: yesEnergies
In recent times, blades that have the ability to change shape passively or actively have garnered interest due to their ability to optimize blade performance for varying flow conditions.
Kyan Sadeghilari, Aditya Atre, John Hall
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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