Results 121 to 130 of about 389,752 (273)

The $B^{+}-B_{d}^{0}$ lifetime difference beyond leading logarithms

, 2002
We compute perturbative QCD corrections to the lifetime splitting between the charged and neutral $B$ meson in the framework of the heavy quark expansion. These next-to-leading logarithmic corrections are necessary for a meaningful use of hadronic matrix
Buchalla, Gerhard, Greub, Christoph, Nierste, Ulrich, Lenz, Alexander, Beneke, Martin   +4 more
core   +2 more sources

Delineation Errors Caused by Replication and Expansion Operations in Monaco

Technology in Cancer Research & Treatment
Background This study aims to investigate the errors in structure volume and shape caused by the replication, expansion, and merging operations of the Monaco system and analyze their influence on dosimetry evaluation.
Dewen Zhang MS, Huarui Yin MS, Ling Xu MS, Wentong Qiu MS, Xianfang Yin MS, Kai Xie MS, Xinye Ni PhD   +6 more
doaj   +1 more source

Sex & marital differences in delayed pharyngeal cancer treatment before and after medicaid expansion

Oral Oncology Reports
Objective: In the United States, pharyngeal cancer has become the most common type of head and neck cancer, with 80 % of cases found in males. Although disparities in treatment delays have been observed in pharyngeal patients, less is known about how ...
Jason Semprini
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A NOVEL STRUCTURAL MONITORING SYSTEM BASED ON A LOW-COST DISPLACEMENT SENSING TECHNIQUE AND IN-SITU CALIBRATION [PDF]

The need for metrological systems with new capacities to perform measurements that go beyond the limits of existing measurement systems is being driven by recent technological advancements and innovation. Structures of machines distort due to thermal and
Chuku, Difference
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Medicaid Expansion and Disparity Reduction in Surgical Cancer Care at High-Quality Hospitals

, 2018
© 2017 American College of Surgeons Background The Affordable Care Act\u27s Medicaid expansion has been heavily debated due to skepticism about Medicaid\u27s ability to provide high-quality care.
Shara, Nawar, Zheng, Chaoyi, Xiao, David, Johnson, Lynt B., Manila Jindal, Chaoyi Zheng, David Xiao, Nawar Shara, Thomas DeLeire, Jindal, Manila, DeLeire, Thomas, Al-Refaie, Waddah B., Lynt B. Johnson, Waddah B. Al-Refaie   +13 more
core   +1 more source