Prognostic Value of Parathyroid Hormone in Heart Failure with Reduced Ejection Fraction. [PDF]
Genç A +3 more
europepmc +1 more source
DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang +7 more
wiley +1 more source
Effect of dapagliflozin on heart failure with reduced ejection fraction in children. [PDF]
Lin S +6 more
europepmc +1 more source
Bio‐Inspired Gradient Coatings Enhance the Leading Edge Erosion Resistance of Wind Blades
Rain‐induced erosion of the wind turbine blade leading edge poses a critical challenge to maintenance and operation. Here, we propose a bio‐inspired approach for erosion protection utilising a platelet‐reinforced polyurethane coating with a graded through‐thickness architecture.
Natalia Sofia Guevara‐Sotelo +2 more
wiley +1 more source
Heart failure with reduced ejection fraction: a systematic review of clinical practice guidelines and recommendations. [PDF]
Datta S +11 more
europepmc +1 more source
Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai +18 more
wiley +1 more source
Inflammatory Biomarkers and ECG Repolarization Metrics: Sudden Death in Heart Failure With Reduced Ejection Fraction. [PDF]
Yogasundaram H +10 more
europepmc +1 more source
A pneumatic energy‐buffering strategy transforms transient and intermittent footsteps into quasi‐continuous electrical energy for a self‐powered wearable biosensing platform. The footwear‐integrated air‐pumping harvester, combined with the rationally designed power‐management system, powers a wearable ankle PPG device with reduced motion artifacts ...
Ji‐Seok Kim +8 more
wiley +1 more source
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han +24 more
wiley +1 more source
Polypill for heart failure with reduced ejection fraction: the POLY-HF randomized trial. [PDF]
Pandey A +18 more
europepmc +1 more source

