Results 181 to 190 of about 4,283,849 (254)

Tumor Mechanical Remodeling via Bidirectional Calcium Redistribution Enables Deep Photothermal‐Immunotherapy

Advanced Science, EarlyView.
A bidirectional calcium‑redistributing nanomodulator rewires intra‑extracellular calcium homeostasis to remodel tumor mechanical microenvironments. It softens tumor stroma to facilitate deep tissue penetration while stiffening tumor cells, evoking amplified immunogenic cell death and robust CTL infiltration, which achieves potent deep photothermal ...
Hongjuan Zhao, Jinpei Sun, Chenxi Zhao, Yuting Cang, Keyu Zong, Yuxin Guo, Yajing Wang, Di Meng, Qingling Song, Lei Wang   +9 more
wiley   +1 more source

Novel biomarkers distinguish heart failure with preserved vs reduced ejection fraction. [PDF]

ESC Heart Fail
Hage C, Mang A, Daubert JC, Donal E, Myhre PL, Linde C, Lund LH.   +6 more
europepmc   +1 more source

Organic Electrochemical Transistors for Neuromorphic Bioelectronics: Materials and Manufacturing Technologies

Advanced Science, EarlyView.
Organic electrochemical transistors bridge biological ionic signaling and neuromorphic computation through volumetric electrochemical gating. This review connects Organic mixed ionic–electronic conductor materials, device architectures, and manufacturing technologies to show how geometry, ion transport, and fabrication strategies program plasticity ...
Hyunjin Lee, Jihyang Park, Xinyi Wang, Yueqi Deng, Jiashu Ren, Tao Zhou   +5 more
wiley   +1 more source

Impaired Cardiac Myosin Super-Relaxation as an Energy-Dissipating Process in Human Heart Failure with Reduced Ejection Fraction. [PDF]

JACC Basic Transl Sci
Ma W, Chaami C, Melhedegaard EG, Lewis CTA, Zhang C, Guo M, Flannagan H, Landim-Vieira M, Pyle WG, Campbell KS, Ochala J.   +10 more
europepmc   +1 more source

Static Drainage H2/O2 PEM Fuel Cells Enabled by Water Transport Plates: Pore‐Scale Design and Transport Mechanisms

Advanced Science, EarlyView.
The WTP is a key component of static drainage PEMFCs, enabling cathode water removal and gas sealing through capillary forces. This work investigates the mechanisms governing WTP drainage and sealing performance and develops predictive approaches for WTP design optimization.
Mengdi Guo, Diankai Qiu, Dong Zhu, Linfa Peng   +3 more
wiley   +1 more source

Hyperaemic effects of adenosine and dobutamine in heart failure with reduced ejection fraction: a quantitative perfusion CMR study. [PDF]

Eur Heart J Imaging Methods Pract
Shergill S, Abdelaty AMSEK, Sedani SR, Moafi A, Athithan L, Bilak JM, Elshibly M, Nehikhare I, Olusan AA, Jaspal P, Hetherington SL, Alama M, Kellman P, Adlam D, Levelt E, Singh A, Squire IB, Hothi SS, Khoo J, Gulsin GS, McCann GP, Arnold JR.   +21 more
europepmc   +1 more source

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source

Stratifying prognosis in heart failure patients with reduced ejection fraction and atrial cardiomyopathy. [PDF]

ESC Heart Fail
Hsu JC, Nadeem U, Kazi K, Hayward C, Mu L, Wong WT, Lip GYH, Petrie MC, Kotecha D, Camm AJ, Wu J, Tse G, Gale CP, Gale CP, Nadarajah R.   +14 more
europepmc   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Correction to: Vericiguat and mortality in heart failure and reduced ejection fraction: the VICTOR trial. [PDF]

Eur Heart J
europepmc   +1 more source