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Heart failure with reduced ejection fraction
Heart failure is a global public health problem that affects more than 26 million people worldwide. The global burden of heart failure is growing and is expected to increase substantially with the ageing of the population. Heart failure with reduced ejection fraction accounts for approximately 50% of all cases of heart failure in the United States and ...
Bloom, Michelle W. +7 more
exaly +8 more sources
Aims The relationship between diabetic microvascular complications and the incidence of two types of heart failure—heart failure with reduced ejection fraction (HFrEF) (left ventricular ejection fraction [LVEF]
Mayu Tochiya +11 more
doaj +1 more source
Vericiguat for Heart Failure with Reduced Ejection Fraction [PDF]
AbstractPurpose of ReviewThe nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) pathway plays an important role in the regulation of cardiovascular function, and it is disrupted in heart failure (HF), resulting in decreased protection against myocardial injury.
Lombardi C. M. +11 more
openaire +4 more sources
The Role of Cardiac Imaging in Heart Failure with Reduced Ejection Fraction
Heart failure (HF) is a major health burden associated with significant morbidity and mortality. Approximately half of all HF patients have reduced ejection fraction (left ventricular ejection fraction
Rebecca C Gosling, Abdallah Al-Mohammad
doaj +1 more source
Aims Left ventricular ejection fraction (LVEF) ≤ 40% is a well‐established risk factor for mortality after acute coronary syndromes (ACS). However, the long‐term prognostic impact of mildly reduced ejection fraction (EF) (LVEF 41–49%) after ACS remains ...
Remo H.M. Furtado +15 more
doaj +1 more source
Therapeutic Stalemate in Heart Failure With Preserved Ejection Fraction
The findings of randomized trials of neurohormonal modulation have been neutral in heart failure with preserved ejection fraction and consistently positive in heart failure with reduced ejection.
Rohan Samson, Thierry H. Le Jemtel
doaj +1 more source
Aims Congestive heart failure (CHF) and impaired renal function are two often co‐existing medical conditions and associated with adverse cardiovascular outcome.
Susanne Jung +8 more
doaj +1 more source
Background The aim of this study was to determine the difference in effects of beta-blockers on long-term clinical outcomes between ischemic heart disease (IHD) patients with mid-range ejection fraction (mrEF) and those with reduced ejection fraction ...
Jun Shitara +12 more
doaj +1 more source
Heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction are associated with significant morbidity and mortality, as well as growing economic burden.
Igor V. Zhirov +2 more
doaj +1 more source
Vitamin D emerged as an important prognostic biomarker in heart failure (HF), with currently highly debated therapeutic implications. Several trials on vitamin D supplementation in HF showed improvements in left ventricular (LV) remodeling and function ...
Timea Magdolna Szabo +8 more
doaj +1 more source

