Results 171 to 180 of about 4,249,295 (316)
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Improving estimation and prediction in linear regression incorporating external information from an established reduced model. [PDF]
Cheng W +4 more
europepmc +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Bu tezde lineer olmayan Schrödinger (NLS) denklemi enerji koruma özelliğine sahip ortalama vektör alanı (OVA) ile çözülmüştür. Ayrıca model indirgeme yöntemi olarak uygun dik ayrışım (UDA) yöntemi uygulanarak bir ve iki boyutlu NLS ve ikili NLS için elde
Akkoyunlu, Canan
core
TArgeted Motion Estimation and Reduction (TAMER): Data Consistency Based Motion Mitigation for MRI Using a Reduced Model Joint Optimization. [PDF]
Haskell MW, Cauley SF, Wald LL.
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Global climate models are very valuable tools in climate sciences and are therefore used in many areas. The applications differ depending on the complexity of the components represented in the model. Three-dimensional physical models of the ocean and the
Ritz, Stefan
core
Reduced model captures Mg(2+)-RNA interaction free energy of riboswitches. [PDF]
Hayes RL +5 more
europepmc +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
A new reduced-order model capable of analyzing the vortex-induced vibration of catenary riser in the ocean current has been developed. This semi analytical-numerical approach is versatile and allows for a significant reduction in computational effort for
, KTP (Funder) +5 more
core

