Results 131 to 140 of about 664,134 (330)
Science of Gymnastics JournalAuxiliary devices are used to train gymnastics skills. Based on the principles of training specificity, this study aimed to investigate the effectiveness of a training device for the static cross posture on Men’s Artistic Gymnastics rings through ...
Paulo Daniel Sabino Carrara +5 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Torsion-Free Modules over Reduced Witt Rings
Journal of Algebra, 2000 For a ring-order \(R\), \textit{R. Wiegand} and \textit{R. Guralnick} [Lect. Notes Pure Appl. Math. 189, 333-347 (1997; Zbl 0884.13004)] defined the genus class group Genus(\(M\)) of a torsion-free, finitely generated \(R\)-module \(M\). The goal of the paper under review is to show that some of these results also hold for the reduced Witt rings of ...
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On Residually Reducible Representations on Local Rings
Journal of Algebra, 1999 Let \(A\) be a local Artinian ring with maximal ideal \(\mathcal M\), let \(R\) be an \(A\)-algebra and let \(\rho\) be an \(A\)-representation of \(R\). If the residual representation \(\overline\rho\) (that is, with values in the residue field) is absolutely irreducible, then it is well-known by a result of Carayol that \(\rho\) is completely ...
openaire +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source