Results 201 to 210 of about 664,134 (330)

Dynamics Model and Its Verification of Aerospace Three-Ring Gear Reducer [PDF]

Jinyong Lai, Lan Luo, Guangzhao Luo, Shiyuan Chao   +3 more
openalex   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Acepromazine Reduces Airway Contraction in a Murine Model of Asthma. [PDF]

Clin Exp Pharmacol Physiol
Lino-Alvarado A, de Oliveira MA, Serra CSM, Melhado IVS, Campos R, Riffo-Vasquez Y, Moriya HT.   +6 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Reduced rank in Noetherian rings

Journal of Algebra, 1979
Chatters, A.W, Goldie, A.W, Hajarnavis, C.R, Lenagan, T.H   +3 more
openaire   +1 more source

SP18. Pelvic Ring Reconstruction With Vascularized Bone Flaps Reduces Compensatory Scoliosis After External Hemipelvectomy

Praneet Paidisetty, Karthik Tappa, Rami Elmorsi, Shalin S. Patel, Justin E. Bird, René D. Largo, Margaret S. Roubaud, Alexander F. Mericli   +7 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Total synthesis of natural products based on hydrogenation of aromatic rings. [PDF]

Beilstein J Org Chem
Wu H, Qi X.
europepmc   +1 more source

Immobilization of Cubic Silver Plasmonic Nanoparticles on TiO₂ Nanotubes, Reducing the Coffee Ring Effect in Surface-Enhanced Raman Spectroscopy Applications

, 2020
Robert Ambroziak, Jan Krajczewski, Marcin Pisarek, Andrzej Kudelski   +3 more
openalex   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source