Results 231 to 240 of about 15,334 (300)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Effect of Ni and Mg incorporation methods into Li₄SiO₄ derived from natural zeolite on CO₂ methanation performance. [PDF]

Sci Rep
Mambetova MM, Yergaziyeva GY, Myltykbayeva LK, Makayeva NM, Anissova MM, Avchukir K, Dossumov K.   +6 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Pt/Al₂O₃ Overcoated with Reactive Metal Oxides and Their Application to Catalytic Oxidation of Propane. [PDF]

Small Methods
Han GH, Koo K, Alayoglu S, W Brown S, M Notestein J.   +4 more
europepmc   +1 more source

Enhanced CO₂ Methanation over Solution-Combustion Synthesized Ni/Kaolin Catalysts: The Effect of Fe and La Promotion. [PDF]

Molecules
Szymaszek-Wawryca A, Hanf S, Szymaszek M, Świerczek K, Duraczyńska D, Marzec M, Motak M.   +6 more
europepmc   +1 more source

EIT-guided end-expiratory pressure individualization in robotic surgery with high PEEP ventilation: a prospective observational study. [PDF]

BMC Anesthesiol
Mihatsch LL, Gnadl A, Harzer F, Rederlechner S, Friederich P.   +4 more
europepmc   +1 more source

CO₂ Methanation on Zeolite/Mesoporous Silica Composites Prepared from Fly Ash and Rice Husk. [PDF]

Nanomaterials (Basel)
Popova M, Theochari G, Szegedi A, Boycheva S, Marinkov N, Karashanova D, Kovacheva D.   +6 more
europepmc   +1 more source