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Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source
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Rational Regulation of Reducibility and Acid Site on Mn–Fe–BTC to Achieve High Low-Temperature Catalytic Denitration Performance

ACS Applied Materials & Interfaces, 2023
Selective catalytic reduction with ammonia is the mainstream technology of flue gas denitration (de-NOx). The reducibility and acid site are two important factors affecting the de-NOx performance, and effective regulation between them is the key to ...
Yonghong Cheng, Jian-Wen Shi
exaly   +2 more sources

Influence of the preparation method in the metal-support interaction and reducibility of Ni-Mg-Al based catalysts for methane steam reforming

open access: yesInternational Journal of Hydrogen Energy, 2019
Ni-Mg-Al based catalysts were prepared using different preparation methods (impregnation, impregnation-coprecipitation and coprecipitation) and tested in steam reforming of methane.
Luis F Bobadilla   +2 more
exaly   +2 more sources

Cu(I) Reducibility Controls Ethylene vs Ethanol Selectivity on (100)-Textured Copper during Pulsed CO2 Reduction.

ACS Applied Materials and Interfaces, 2021
The electrochemical CO2 reduction reaction (CO2RR) can convert widely available CO2 into value-added C2 products, such as ethylene and ethanol. However, low selectivity toward either compound limits the effectiveness of current CO2RR electrocatalysts ...
Zhichu Tang   +4 more
semanticscholar   +1 more source

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