Results 111 to 120 of about 7,615,514 (366)

C no more: a prospective single-arm study to evaluate the effectiveness of a nurse and peer-led mobile model of hepatitis C testing and treatment at community corrections offices

open access: yesHealth & Justice
Background The community corrections population in Australia shares similar risk factors for hepatitis C virus (HCV) infection with people incarcerated in prisons, but without access to prison-based testing and treatment.
Samara Griffin   +14 more
doaj   +1 more source

Global state of harm reduction 2018. [PDF]

open access: yes, 2018
The 2018 Global State of Harm Reduction report contains information on: • The number of people who inject drugs and the number of people imprisoned for drug use (where data is available).
Shirley-Beavan, Sam, Stone, Katie
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Socioeconomic and Data challenges Disaster Risk Reduction in Europe

open access: yes, 2019
Disaster risk reduction (DRR) involves complex processes with different stakeholders at all administrative levels. Two elements in particular play a major role: the need to ensure stakeholders' interoperability through an efficient exchange of data, and ...
Hagen, Jenny Sjastad   +21 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Topography of Area Adjacet to Caselton Shaft ; Combined Metals Reduction Company [03]

open access: yes, 1937
Combined Metals Reduction Company ; Pioche, Nevada ; Topography of Area Adjacent to Caselton ...
Combined Metals Reduction Company
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

PERFORMANCE OPTIMIZATION AND MOLECULAR DYNAMICS MECHANISM OF COMPOSITE INSULATING SILICONE RUBBER AFTER ELECTRIC HEATING POST-TREATMENT

open access: yesMateriali in Tehnologije
This study investigates the optimization of composite silicone rubber (SR) through a physical electrothermal post-treatment process that functions as an efficient structural annealing method.
Pengkang Xie   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Topography of Area Adjacet to Caselton Shaft ; Combined Metals Reduction Company [02]

open access: yes, 1937
Combined Metals Reduction Company ; Pioche, Nevada ; Topography of Area Adjacent to Caselton ...
Combined Metals Reduction Company
core  

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