Results 111 to 120 of about 17,825,014 (339)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

River rejuvenation on a fluvial fan induced by typhoons and earthquakes

open access: yesnpj Natural Hazards
This study investigates decadal-scale river rejuvenation and migration in Taiwan’s Mu-Gua River watershed, influenced by typhoons and earthquakes. Typhoon Ofelia (1990) caused rapid sediment aggradation and channel instability, leading to severe damage ...
Jui-Yi Ho   +6 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Fire evacuation strategies for traditional public markets in an aging society

open access: yesCase Studies in Thermal Engineering
Traditional public markets in Taiwan are unique in that they mimic markets in traditional agricultural societies, offering convenient access to diverse goods and services.
Chih-Hao Hsu, Carol C. Wu, Kai-Min Liao
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Experimental and numerical study on axial compressive strength of waste carbon fibre-reinforced concrete

open access: yesLow-Carbon Materials and Green Construction
The integration of waste carbon fibre materials, specifically shredded prepreg carbon cloth waste (SPCCW) and discarded carbon fibre-reinforced polymer (DCFRP), presents a sustainable and innovative approach to enhancing the structural performance of ...
Umar Ayaz Lone   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Study on Enhancing the Comprehensive Prevention Capability of Marine Disasters in Shandong Province

open access: yesHaiyang Kaifa yu guanli
Shandong Province, one of the regions in China most severely affected by marine disasters, faces multiple challenges including diverse disaster types, extensive geographical distribution, high frequency of occurrence, and significant economic losses ...
JI Chengzhen   +5 more
doaj  

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.

open access: yesNew England Journal of Medicine, 2002
W. Knowler   +6 more
semanticscholar   +1 more source

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