Results 71 to 80 of about 9,799,480 (312)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Downscaling Taiwan precipitation with a residual deep learning approach

Geoscience Letters
In response to the growing demand for high-resolution rainfall data to support disaster prevention in Taiwan, this study presents an innovative approach for downscaling precipitation data.
Li-Huan Hsu, Chou-Chun Chiang, Kuan-Ling Lin, Hsin-Hung Lin, Jung-Lien Chu, Yi-Chiang Yu, Chin-Shyurng Fahn   +6 more
doaj   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

What Goes Around: the process of building a community-based harm reduction research project

Harm Reduction Journal, 2017
Background Often, research takes place on underserved populations rather than with underserved populations. This approach can further isolate and stigmatize groups that are already made marginalized. What Goes Around is a community-based research project
Chelsea Jalloh, Shohan Illsley, John Wylie, Paula Migliardi, Ethan West, Debbie Stewart, Javier Mignone   +6 more
doaj   +1 more source

Reductive evolution and genomic reduction in Rhodopseudomonas

Applied and Environmental Microbiology
ABSTRACT Rhodopseudomonas palustris is renowned for its metabolic versatility, supported by a genome that contains pathways for numerous processes. In a recent study, Oda et al.
Brian M. Gallagher, Hailee M. Morrison, Arpita Bose   +2 more
openaire   +2 more sources

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Expanding access to harm reduction in rural communities through community-informed public health vending machines

Harm Reduction Journal
Background The opioid epidemic continues to disproportionately impact rural communities across the United States, where structural barriers, including geographic isolation, limited public health infrastructure, and heightened stigma, restrict access to ...
Lori Ann Eldridge, Christian Dotson, Lauren Harrell, Marcus Berry, Samantha Bradley, Alicia Brunelli, Jane Casarez, Virginia Fagg, Wendy Odum, Amanda McKenna-Williams, Kathleen L. Egan   +10 more
doaj   +1 more source

Optimal Allocation of Fire Extinguishing Equipment for a Power Grid Under Widespread Fire Disasters

IEEE Access, 2018
Widespread fire disasters always occur in several concentrated short periods. A large range of fire disasters can cause the tripping of dozens of transmission lines simultaneously, posing a serious threat to safe operation of the power grid.
Jiazheng Lu, Jun Guo, Zhou Jian, Xunjian Xu   +3 more
doaj   +1 more source