Results 191 to 200 of about 5,134,770 (327)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Pain as Lived Experience: Philosophical Perspectives in Pain Medicine - A Narrative Review. [PDF]

J Pain Res
Shin DA, Chang MC.
europepmc   +1 more source

Buddhist Error Theory [PDF]

, 2020
Hidalgo, Javier
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Editorial: Deepening consciousness: what phenomenology, yogic, and Buddhist meditation can contribute from a psychological perspective. [PDF]

Front Psychol
Gutland C, di Fronso S, Schleim S.
europepmc   +1 more source

A Novel Approach to Emergence in Chemistry [PDF]

, 2015
A Manafu, A Vicente, AM Turing, CD Broad, D Papineau, D Papineau, E Nagel, E Scerri, E Scerri, E Scerri, H Kincaid, H Putnam, H Zeh, J Kim, J-P Llored, JA Fodor, JS Mill, L McIntyre, O Lombardi, P Humphreys, P Humphreys, P Humphreys, P Janich, P Kitcher, P Kitcher, PL Luisi, R Woolley, RF Hendry, RF Hendry, RF Hendry, RF Hendry, RW Batterman, RW Batterman, S Gibb, SL Adler   +34 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

From reductionism to complex systems: Paradigm shift and knowledge evolution in competitive sports research using BERTopic. [PDF]

PLoS One
Pan L.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The human biological clock and aging-a comprehensive approach integrating reductionism, holism, and geromedicine for proactive healthspan strategies. [PDF]

Front Aging
Phua TJ.
europepmc   +1 more source