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On the Inheritance of Microbiome-Deficiency: Paediatric Functional Gastrointestinal Disorders, the Immune System and the Gut–Brain Axis

open access: yesGastrointestinal Disorders, 2023
Like the majority of non-communicable diseases that have recently gained attention, functional gastrointestinal (GI) disorders (FGID) in both children and adults are caused by a variety of medical conditions.
David Smith   +5 more
doaj   +1 more source

Hypoxia-inducible transcription factor-1α inhibition by topotecan protects against lipopolysaccharide-induced inflammation and apoptosis of cardiomyocytes

open access: yesBioMedical Engineering OnLine, 2021
Background Myocarditis, an inflammatory disease of the myocardium, is a serious hazard to human life due to the expansion of inflammatory lesions in the myocardium.
Ying Zhang   +5 more
doaj   +1 more source

Macrophage morphological plasticity and migration is Rac signalling and MMP9 dependant

open access: yesScientific Reports, 2021
In vitro, depending on extracellular matrix (ECM) architecture, macrophages migrate either in amoeboid or mesenchymal mode; while the first is a general trait of leukocytes, the latter is associated with tissue remodelling via Matrix Metalloproteinases ...
Jana Travnickova   +6 more
doaj   +1 more source

Design methods for riding behavior-based collision avoidance systems (Structural equation modeling and decision tree analysis)

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2023
This study focused on demonstrating how to design riding behavior-based collision avoidance systems (RB-CAWS). Statistical and machine learning algorithms were adopted and analyzed previously collected data from the riding simulator-based experiments ...
Kifle Hailu GEBRETSADIK   +2 more
doaj   +1 more source

Treatment of status epilepticus in pediatrics: curriculum learning combined with in-situ simulations

open access: yesBMC Medical Education, 2022
Background Appropriate and timely treatment of status epilepticus (SE) reduces morbidity and mortality. Therefore, skill-based identification and management are critical for emergency physicians.
Huiping Wei   +7 more
doaj   +1 more source

Analysis of Consultations that are Requested from the Emergency Department

open access: yesCam & Sakura Medical Journal, 2021
Objective: Emergency departments (EDs) are medical units that provide healthcare to patients with diseases that have sudden onset symptoms, patients with disorders, or patients with injuries that need immediate care on a 24/7 basis.
Kemal Şener   +3 more
doaj   +1 more source

Prognostic and diagnostic importance of the systemic immune-inflammation index in pediatric head trauma

open access: yesMedicine Science, 2023
Head trauma is a leading cause of mortality and morbidity in pediatric patients. The trauma itself leads to the activation of a biomolecular cascade of damage.
Kemal Sener   +6 more
doaj   +1 more source

Tularemia: emergence/re-emergence [PDF]

open access: yesVeterinary Research, 2005
Francisella tularensis is a gram-negative coccobacillus and the etiologic agent of the zoonotic disease tularemia. First described in 1911 in Tulare County, California, it has since been reported throughout the Northern Hemisphere, with natural infections reported among an unusually wide range of vertebrates and invertebrates.
Petersen, Jeannine M.   +1 more
openaire   +3 more sources

Naturally acquired Mycobacterium tuberculosis complex in laboratory pig-tailed macaques

open access: yesEmerging Microbes and Infections, 2012
Here we present a case series from a primate research facility. The index case, a 4-year-old pig-tailed macaque (Macaca nemestrina) experimentally infected with chimeric simian-human immunodeficiency virus (SHIV SF162 P4 ), developed weight loss and was ...
Gregory A Engel   +5 more
doaj   +1 more source

Emerging and Re-Emerging Diseases [PDF]

open access: yesPathogens, 2021
Throughout history, infectious diseases have vastly impacted human civilization [...]
Wen-Hung Wang   +3 more
openaire   +3 more sources

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