Results 51 to 60 of about 67,395 (285)

Critical Discourse Analysis of Spontaneous Urban Settlements in the World and Iran [PDF]

open access: yesبرنامه‌ریزی توسعه شهری و منطقه‌ای, 2019
After the industrialization period, the phenomenon of poverty has been gradually replaced by spatial rotation and in the framework of the transition from rural and industrial phenomena to urban phenomena, and by reaching the second step of capital ...
Kasra Ashouri   +2 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

A Journey from Reductionism in Neuroscience to Reductionism in Psychiatry

open access: yesInternational Journal of Body, Mind and Culture, 2015
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Fahimeh Mianji
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Multidimensional Properties: Primitivism vs Reductionism

open access: yesMetaphysics
The focus of this paper is on the metaphysical nature of multidimensional properties, properties like virtue, beauty, or health which can be had in different ways and to different degrees.
Robert Michels
doaj   +1 more source

ФІЛОСОФІЯ ДЕКАРТА: БАЗОВА ІНТЕНЦІЯ ТА СТАТУС АНТРОПОЛОГІЇ

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2013
Мета. Мета даної статті – наголосити на недостатності редукціоністських тлумачень спадщини Декарта та акцентувати конститутивну значимість антропології у власному проекті мислителя. Методологія. Звертання до феноменології та герменевтики надає можливість
Anatolii M. Malivskyi
doaj   +1 more source

Complexity and Philosophy [PDF]

open access: yes, 2006
The science of complexity is based on a new way of thinking that stands in sharp contrast to the philosophy underlying Newtonian science, which is based on reductionism, determinism, and objective knowledge.
Cilliers, Paul   +2 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Examine the effects Reductionism thinking oriented, and contrast it with Bionic design oriented problems [PDF]

open access: yesJilvah-i hunar, 2014
This article discusses how thinking how to design issues-oriented approach to subside and by examining the question of the scope of or in opposition to subside oriented discussion Holism that idea in the world is Reductionism to integration, be applied ...
سمیه حجازی
doaj   +1 more source

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