Results 161 to 170 of about 2,999 (176)
Some of the next articles are maybe not open access.
NADPH-Driven Organohalide Reduction by a Nonrespiratory Reductive Dehalogenase
Biochemistry, 2018Reductive dehalogenases are corrinoid and iron-sulfur cluster-dependent enzymes that mostly act as the terminal oxidoreductases in the bacterial organohalide respiration process. This process often leads to detoxification of recalcitrant organohalide pollutants.
Fraser A. Collins +5 more
openaire +3 more sources
Heterologous Production of Functional Chloroform Reductive Dehalogenase
The FASEB Journal, 2017Background Reductive dehalogenases (RDase) are key enzymes involved in the respiratory process of anaerobic organohalide respiring bacteria (ORB). RDases are membrane‐associated proteins whose activity is dependent on protein‐associated cobalamin and iron‐sulfur clusters.
Bat‐Erdene Jugder +6 more
openaire +1 more source
Reductive Dehalogenase Structures
Chemical & Engineering News Archive, 2014In recent weeks, two independent teams have reported long-sought X-ray crystal structures of two enzymes that remove halides from molecules with help from vitamin B-12. These so-called reductive dehalogenase enzymes enable some bacteria to breathe organohalides like other organisms breathe oxygen.
openaire +1 more source
Bacterial Reductive Dehalogenases
2004Toxic halogenated organic compounds can originate from both natural (Gribble 1994, 1996) and industrial sources (Fetzner 1998; Mohn and Tiedje 1992). Many industrially produced polyhalogenated organic compounds such as pentachlorophenol (PCP), polychlorinated biphenyls (PCBs), perchloroethylene (PCE), trichloroetheylene (TCE) and dichloromethane (DCM ...
Marc B. Habash +2 more
openaire +1 more source
Heterologous Production and Purification of a Functional Chloroform Reductive Dehalogenase
ACS Chemical Biology, 2018Reductive dehalogenases (RDases) are key enzymes involved in the respiratory process of anaerobic organohalide respiring bacteria (ORB). Heterologous expression of respiratory RDases is desirable for structural and functional studies; however, there are few reports of successful expression of these enzymes. Dehalobacter sp.
Bat-Erdene Jugder +8 more
openaire +3 more sources
Applied and Environmental Microbiology, 2022
Understanding microbial reductive dehalogenation is important to refine the global halogen cycle and to improve bioremediation of halogenated contaminants; however, studies of the family of enzymes responsible are limited. Characterization of reductive dehalogenase enzymes has largely eluded researchers due to the lack of a reliable and high-yielding ...
Katherine J. Picott +2 more
openaire +2 more sources
Understanding microbial reductive dehalogenation is important to refine the global halogen cycle and to improve bioremediation of halogenated contaminants; however, studies of the family of enzymes responsible are limited. Characterization of reductive dehalogenase enzymes has largely eluded researchers due to the lack of a reliable and high-yielding ...
Katherine J. Picott +2 more
openaire +2 more sources
Reductive Dehalogenases Come of Age in Biological Destruction of Organohalides
Trends in Biotechnology, 2015Halogenated organic compounds (organohalides) are globally prevalent, recalcitrant toxic, and carcinogenic environmental pollutants. Select microorganisms encode enzymes known as reductive dehalogenases (EC 1.97.1.8) that catalyze reductive dehalogenation reactions resulting in the generation of lesser-halogenated compounds that may be less toxic and ...
Bat-Erdene, Jugder +4 more
openaire +2 more sources
Archives of Microbiology, 2006
Sulfurospirillum multivorans is a dehalorespiring organism, which is able to utilize tetrachloroethene as terminal electron acceptor in an anaerobic respiratory chain. The localization of the tetrachloroethene reductive dehalogenase in dependence on different growth substrates was studied using the freeze-fracture replica immunogold labeling technique.
Markus, John +4 more
openaire +2 more sources
Sulfurospirillum multivorans is a dehalorespiring organism, which is able to utilize tetrachloroethene as terminal electron acceptor in an anaerobic respiratory chain. The localization of the tetrachloroethene reductive dehalogenase in dependence on different growth substrates was studied using the freeze-fracture replica immunogold labeling technique.
Markus, John +4 more
openaire +2 more sources
Purification and characterization of the tetrachloroethene reductive dehalogenase of strain PCE-S
Archives of Microbiology, 1998The membrane-associated tetrachloroethene reductive dehalogenase from the tetrachloroethene-reducing anaerobe, strain PCE-S, was purified 165-fold to apparent homogeneity in the presence of the detergent Triton X-100. The purified dehalogenase catalyzed the reductive dechlorination of tetrachloroethene to trichloroethene and of trichloroethene to cis-1,
E, Miller, G, Wohlfarth, G, Diekert
openaire +2 more sources
Insights into Reductive Dehalogenase Function Obtained from Crystal Structures
2016Reductive dehalogenases are a class of corrinoid and [4Fe–4S] cluster-dependent enzymes that are arguably key to organohalide respiration. Recently, the first crystal structures for these enzymes were reported, including one representative of both a respiratory as well as a nonrespiratory catabolic reductive dehalogenase.
Holger Dobbek, David Leys
openaire +1 more source