Results 81 to 90 of about 865,993 (309)
A high reliability battery management system [PDF]
, 1986 Over a period of some 5 years Canadian Astronautics Limited (CAL) has developed a system to autonomously manage, and thus prolong the life of, secondary storage batteries.
Moody, M. H.
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Triple redundant computer system/display and keyboard subsystem interface [PDF]
Interfacing of the redundant display and keyboard subsystem with the triple redundant computer system is defined according to space shuttle design. The study is performed in three phases: (1) TRCS configuration and characteristics identification; (2 ...
Gulde, F. J.
core +1 more source
Conceptual nonorthogonal gyro configuration for guidance and navigation [PDF]
, 1967 Nonorthogonal sensor configuration using six single-degree-of-freedom inertial reference gyroscopes and a complete data processing and self-contained failure detection-and-isolation mechanism provides redundant capabilities to guidance and navigation ...
Gilmore, J. P.
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Airborne Advanced Reconfigurable Computer System (ARCS) [PDF]
A digital computer subsystem fault-tolerant concept was defined, and the potential benefits and costs of such a subsystem were assessed when used as the central element of a new transport's flight control system.
Bjurman, B. E. +4 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Design of CRH2 EMUs Control System Redundant Safety
机车电传动, 2019 Aiming at the characteristics of high safety and reliability of the CRH2 EMUs vehicle control system, the communication architecture of network control system, software and hardware control platform and vehicle electrical control system was studied.
Qunxin LIU, Fang HUO
doaj
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source