We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
On Ergodic and Inverse Shadowing Properties of Set-Valued Mapping. [PDF]
Wattan Kamil F, Al-Shara'a IMT.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Interrogating alignment of the 2026 FIFA World Cup event objectives across the Canadian soccer system. [PDF]
Teare G, Morrison KA, Bodin KL.
europepmc +1 more source
MEDICATION ADHERENCE AMONG ELDERLY PATIENTS RECEIVING HEALTH CARE SERVICES IN WATERBERG DISTRICT, LIMPOPO PROVINCE: A Qualitative phenomenological study protocol. [PDF]
Mavhungu T, Mudau AG, Lebese TR.
europepmc +1 more source
openaire +1 more source
Trait emotional intelligence in competitive sports: are there differences in dimensions of emotional intelligence when comparing different sports? [PDF]
Kopp A, Jekauc D.
europepmc +1 more source
Simultaneous Numerical Determination of Two Time-dependent Coefficients in Second Order Parabolic Equation With Nonlocal Initial and Boundary Conditions. [PDF]
A J Al-Shatrah M, Sabah Hussein M.
europepmc +1 more source
The FIFA 11 + Referees program improves knee proprioception in female futsal referees. [PDF]
Khosravi Rad F +3 more
europepmc +1 more source

