Results 121 to 130 of about 1,078,089 (249)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Larger Real-World OCT Reference Database Improves Accuracy of Glaucoma Flagging Using Summary Metrics. [PDF]

Transl Vis Sci Technol
Hood DC, Durbin M, Lee C, Guzman A, Gebhardt T, Wang Y, De Moraes CG, Tsamis E.   +7 more
europepmc   +1 more source

Cynomolgus monkey's retina volume reference database based on hybrid deep learning optical coherence tomography segmentation. [PDF]

Sci Rep, 2023
Denk N, Freichel C, Valmaggia P, Inglin N, Scholl HPN, Kaiser P, Wise S, Vezina M, Maloca PM.   +8 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

ParaRef: a decontaminated reference database for parasite detection in ancient and modern metagenomic datasets. [PDF]

Genome Biol
Niemann J, Huang Y, Lanigan LT, Willingham Grijalba AL, Dunn RR, Sikora M, Schroeder H.   +6 more
europepmc   +1 more source

Use of a taxon-specific reference database for accurate metagenomics-based pathogen detection of Listeria monocytogenes in turkey deli meat and spinach. [PDF]

BMC Genomics, 2023
Rumore J, Walker M, Pagotto F, Forbes JD, Peterson CL, Tyler AD, Graham M, Van Domselaar G, Nadon C, Reimer A, Knox N.   +10 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

DiazoTIME: a metabolically-resolved reference database of nitrogen-fixing microbial genomes. [PDF]

Microbiol Resour Announc
Damashek J, Sheik CS, Petro C, Reeder CF, Chowdhury S, Kramer BJ, DeVilbiss SE, Pierella Karlusich JJ, Marks JC, Valdespino-Castillo PM, Furey PC, Berberich ME, Marcarelli AM, Scott JT, Fulweiler RW.   +14 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Curated mitochondrial genome reference database of state key protected wild mammal in China. [PDF]

PLoS One
Huang X, Zhang G, Orkin JD, Liu S, Jiang S, Zhao Y, Fan P, Huang L, Zhang X, Li X, Li S, He K.   +11 more
europepmc   +1 more source