Results 101 to 110 of about 15,634,829 (260)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Antea Group Archeologie 2017/154

open access: yes, 2020
Antea projectnummer 419284 In september en oktober 2017 heeft Antea Group een archeologische begeleiding uitgevoerd ter plaate van een gasleidingtracé in de omgeving van Niehove (gemeente Zuidhorn): twee wierdeterreinen bij Frytum, één bij Enuma en een ...
Fens, R. (Antea Group)   +1 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Antea Group Archeologie 2016/54

open access: yes, 2018
In opdracht van de gemeente Waalwijk heeft Antea Group in 2016 een archeologisch bureauonderzoek uitgevoerd naar de beschikbare archeologische gegevens met betrekking tot de Havenzone ten zuiden van de Rijksweg A59 te Waalwijk.
Koopmanschap, Dr. H.J.L.C. (Antea Group)
core   +1 more source

Passenger lymphocyte syndrome – epidemiology, pathogenesis, diagnosis, treatment and future directions: A review

open access: yesBiomolecules & Biomedicine
Passenger lymphocyte syndrome (PLS) is a hematological complication that can occur following transplantation, characterized by donor-derived memory B lymphocytes producing antibodies against the recipient's blood cells.
Yingfang Pan   +6 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Outstanding Business Reference Sources 2013

open access: yes, 2014
A selection of business reference sources for ...
BRASS Business Reference Sources Committee
core  

Antea Group Archeologie 2019/141

open access: yes, 2020
Antea Group projectnummer 431766 Antea Group heeft op 9, 10 en 19 april 2018 een archeologisch inventariserend veldonderzoek uitgevoerd op de wierde Groot Maarslag in de gemeente Het Hogeland.
Tuinstra, S.J. (Antea Group)   +1 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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