Results 221 to 230 of about 5,447,975 (305)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Comprehensive, Quantitative Analysis of SRM 1950: the NIST Human Plasma Reference Material. [PDF]

Anal Chem
Mandal R, Zheng J, Zhang L, Oler E, LeVatte MA, Berjanskii M, Lipfert M, Han J, Borchers CH, Wishart DS.   +9 more
europepmc   +1 more source

Fundamental studies to develop certified reference material to calibrate spectrophotometer in the ultraviolet region [PDF]

, 2016
F C da Conceição, Paulo Paschoal Borges, Juliana Freitas Santos Gomes   +2 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Is commutability of a reference material always desirable? [PDF]

J Mass Spectrom Adv Clin Lab
Vogeser M, Habler K.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Establishment of Reference Measurement Procedure for <i>TP53</i> R175H/R248W Detection and a Novel Preparation Method for ctDNA Reference Material. [PDF]

Genes (Basel)
Tang Y, Niu C, Zhang J, Dong L, Yang J.
europepmc   +1 more source

Biotite Reference Materials for Secondary Ion Mass Spectrometry ¹⁸O/¹⁶O Measurements

, 2016
Guillaume Siron, Lukas P. Baumgartner, Anne‐Sophie Bouvier, Benita Putlitz, Torsten Vennemann   +4 more
openalex   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

SI-traceable characterisation of the first reference material for nanoparticle number concentration in suspension to support regulatory compliance. [PDF]

Anal Bioanal Chem
Bartczak D, Nuñez SC, Kubicka A, Ojeda D, Cachero AS, Cowen S, Ellison S, Holcombe G, Goenaga-Infante H.   +8 more
europepmc   +1 more source