Results 241 to 250 of about 18,697,629 (340)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Digital PCR Validation for Characterization of Quantitative Reference Material of Escherichia coli O157:H7 Genomic DNA. [PDF]

Methods Protoc
Tere-Peña CP, Calderon-Ozuna MN, Leguizamón Guerrero JE.   +2 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Powder Metallurgy Processing to Enhance Superelasticity and Shape Memory in Polycrystalline Cu-Al-Ni Alloys: Reference Material for Additive Manufacturing. [PDF]

Materials (Basel)
Pérez-Cerrato M, Gómez-Cortés JF, Urionabarrenetxea E, Ruiz-Larrea I, Carreño F, Ayesta Í, Nó ML, Burgos N, San Juan JM.   +8 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors. [PDF]

Metabolomics
Cruz AK, Alves MA, Andresson T, Bayless AL, Bloodsworth KJ, Bowden JA, Bullock K, Burnet MC, Neto FC, Choy A, Clish CB, Couvillion SP, Cumeras R, Dailey L, Dallmann G, Davis WC, Deik AA, Dickens AM, Djukovic D, Dorrestein PC, Eder JG, Fiehn O, Flores R, Gika H, Hagiwara KA, Pham TH, Harynuk JJ, Aristizabal-Henao JJ, Hoyt DW, Jean-François F, Kråkström M, Kumar A, Kyle JE, Lamichhane S, Li Y, Nam SL, Mandal R, de la Mata AP, Meehan MJ, Meikopoulos T, Metz TO, Mouskeftara T, Munoz N, Gowda GAN, Orešic M, Panitchpakdi M, Pierre-Hugues S, Raftery D, Rushing B, Schock T, Seifried H, Servetas S, Shen T, Sumner S, Carrillo KST, Thibaut D, Trejo JB, Van Meulebroek L, Vanhaecke L, Virgiliou C, Weldon KC, Wishart DS, Zhang L, Zheng J, Da Silva S.   +64 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Ions with Ions, Entities with Entities: A Proof-of-Concept Study Using the SELM-1 Yeast Certified Reference Material for Intra- and Extracellular Se Quantification via Single-Cell ICP-Mass Spectrometry. [PDF]

Anal Chem
Bazo A, Bolea-Fernandez E, Rua-Ibarz A, Aramendía M, Resano M.   +4 more
europepmc   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source