Results 211 to 220 of about 11,306,421 (294)

Can Reference Materials Prepared Following CLSI C37-A Be Utilized Without Commutability Assessment? Perspectives Based on Lipid Measurements. [PDF]

Ann Lab Med
Seo JD, Kwon GC, Kim JH, Lee SG, Song J, Park PW, An D, Choi Q, Cho CI, Kim S, Yun YM.   +10 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Lyophilized T Cell Reference Materials with Quantified Proportions of Subtypes. [PDF]

ACS Omega
Huo Y, Yang J, Wen Y, Liang W, Tao Q, Yan J, Xu H, Li L, Li Y, Xu L, Ding M, Gong F, Liu G.   +12 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

From Expert Knowledge to Validation Resources: A Case for Using in Silico Approaches to Close the Gap in Available Reference Materials for Common Germline Genetic Tests. [PDF]

J Mol Diagn
Roy S, Tremblay MW, Lockhart E, Aradhya S, Bayrak-Toydemir P, Bowser M, DaRe J, Gibson K, Kennemer M, Krueger C, Lebo M, Mao R, Nussbaum R, O'Fallon B, Rosato A, Kalman LV, Funke B.   +16 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Interlaboratory assessment of candidate reference materials for lentiviral vector copy number and integration site measurements. [PDF]

Mol Ther Methods Clin Dev
He HJ, He Z, Lund SP, Turner L, Fan Y, Qiu Y, Corney DC, Dropulic B, Orentas R, Slessareva O, Welch P, Dungca K, Stelloo E, Dijksteel G, Feitsma H, Ahmed-Seghir S, Makarenko R, Altunlu E, Steenmans D, Spanholtz J, Raimo M, Senderovich S, Paugh BS, Li CY, Schroeder B, Whale AS, Yener D, Foy CA, Nahas S, Tu F, Sheldon M, Ding Y, Kandell J, Lakshmipathy U, McDaniel JH, Zook JM, Miller S, Maragh S, Patange S, Mohiuddin M, Tona A, Cole KD, Lin-Gibson S.   +42 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Advancing Accuracy in Chronic Kidney Disease Diagnosis and Management: Reference Materials and Reference Measurement Procedures for Clinical Markers. [PDF]

Ann Lab Med
Tan HT, Liu Q, Teo TL.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source