Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Hurricanes, Neighborhood Disadvantage, and Cardiopulmonary Health in US Veterans.
Yip CS +4 more
europepmc +1 more source
Socioeconomic and geographic inequalities in unmet healthcare needs in Cambodia: evidence from a national cross-sectional study. [PDF]
Maung KT +4 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Changes in health-related social needs and in depression and anxiety symptoms in Massachusetts low-income, community health center patients: an observational cohort study. [PDF]
Wu Y +6 more
europepmc +1 more source
Correction to: Towards cleaner environment: recycling microalgal co-product to reduce emissions and impacts while eliminating fishmeal in rainbow trout feed for sustainable aquaculture. [PDF]
Sarker PK +12 more
europepmc +1 more source
Leveraging large language models to maintain a branded food product database. [PDF]
Hauff P, Krems C, Kohl J.
europepmc +1 more source
Exploring the need for a social prescribing pathway in an Australian paediatric allied healthcare intake service: a pilot feasibility and acceptability study. [PDF]
Hamill L +10 more
europepmc +1 more source
Potential of real-time pollen data: perceived needs and symptom management among seasonal allergic rhinitis patients. [PDF]
van Gaal N +3 more
europepmc +1 more source

