Results 221 to 230 of about 9,933,382 (352)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Investigation of the Precision in Geodetic Reference-Point Positioning Because of Temperature-Induced Pillar Deflections. [PDF]

Sensors (Basel), 2019
Močnik R, Koler B, Zupan D, Ambrožič T.   +3 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Microhardness distribution of the tibial diaphysis and test site selection for reference point indentation technique. [PDF]

Medicine (Baltimore), 2019
Wang J, Yin B, Liu G, Li S, Zhang X, Hu Z, Wu W, Zhang Y.   +7 more
europepmc   +1 more source

Determination of the Depth- and Time- Dependent Mechanical Behavior of Mouse Articular Cartilage Using Cyclic Reference Point Indentation. [PDF]

Cartilage, 2020
Chang A, Tang SY.
europepmc   +1 more source

Comparative evaluation of the most reliable posterior reference point of Camper′s plane in relation with hamular notch-incisive papilla plane with change in gender of edentulous subjects: A cephalometric study

, 2016
Kirandeep Kaur, Santosh Nelogi, Raghunath Patil   +2 more
openalex   +1 more source

Change of perspective: bibliometrics from the point of view of cited references—a literature overview on approaches to the evaluation of cited references in bibliometrics [PDF]

, 2016
Werner Marx, Lutz Bornmann
openalex   +1 more source

Reference point insensitive molecular data analysis

Bioinform., 2017
M. Altenbuchinger, T. Rehberg, H. Zacharias, Frank Stämmler, K. Dettmer, D. Weber, A. Hiergeist, A. Gessner, Ernst Holler, P. Oefner, R. Spang   +10 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Clinical measurements of bone tissue mechanical behavior using reference point indentation. [PDF]

Clin Rev Bone Miner Metab, 2018
Chang A, Easson GW, Tang SY.
europepmc   +1 more source