Results 111 to 120 of about 7,574,742 (332)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Defining ecosystem thresholds for human activities and environmental pressures in the California Current

Ecosphere, 2017
The oceans are changing more rapidly than ever before. Unprecedented climatic variability is interacting with unmistakable long‐term trends, all against a backdrop of intensifying human activities.
Jameal F. Samhouri, Kelly S. Andrews, Gavin Fay, Chris J. Harvey, Elliott L. Hazen, Shannon M. Hennessey, Kirstin Holsman, Mary E. Hunsicker, Scott I. Large, Kristin N. Marshall, Adrian C. Stier, Jamie C. Tam, Stephani G. Zador   +12 more
doaj   +1 more source

Reference dependence and market competition [PDF]

, 2008
This paper studies the implications of consumer reference dependence for market competition. If consumers take some product (e.g., the first product they consider) as the reference point when evaluating others and exhibit loss aversion, then the more ...
Zhou, J., Zhou, Jidong
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Biological reference points to support the choice of Minimum Conservation Reference Size for the king scallop, Pecten maximus, in Welsh Waters

Natalie Hold, Jack Egerton, Leven Tom Brendan, Philip R. Hollyman   +3 more
  +4 more sources

Evolutionary dynamics in financial markets with heterogeneities in investment strategies and reference points. [PDF]

PLoS One, 2023
Xu WJ, Zhong CY, Ren F, Qiu T, Chen RD, He YX, Zhong LX.   +6 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Expectations, reference points, and compliance with COVID-19 social distancing measures. [PDF]

J Behav Exp Econ, 2023
Briscese G, Lacetera N, Macis M, Tonin M.   +3 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Methodology for developing metrics to measure the effectiveness of triggers and customer interaction in modern marketing theory

Innovation and Sustainability
The article discusses the topical issue of measuring the effectiveness of triggers and customer interaction in modern marketing theory. Particular attention is paid to the integration of qualitative and quantitative approaches to assessing the ...
V. Bobrovnyk, Z. Andrushkevych
doaj   +1 more source