Results 91 to 100 of about 1,472,977 (260)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Response: Commentary: Stock Status Assessments for 12 Exploited Fishery Species in the Tsushima Warm Current Region, Southwest Japan and East China, Using the CMSY and BSM Methods

open access: yesFrontiers in Marine Science, 2022
Yuanchao Wang   +10 more
doaj   +1 more source

Fish Stock Assessment Models for Developing Nations with Emphasis on the Use of the Classic Gordon–Schaefer Model: A Review

open access: yesFishes
The paper discusses fish stock assessment methods, emphasising methods for assessing stocks in developing nations. We present the advantages and disadvantages of each method discussed.
Francisco Chamera   +5 more
doaj   +1 more source

Defining ecosystem thresholds for human activities and environmental pressures in the California Current

open access: yesEcosphere, 2017
The oceans are changing more rapidly than ever before. Unprecedented climatic variability is interacting with unmistakable long‐term trends, all against a backdrop of intensifying human activities.
Jameal F. Samhouri   +12 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Methodology for developing metrics to measure the effectiveness of triggers and customer interaction in modern marketing theory

open access: yesInnovation and Sustainability
The article discusses the topical issue of measuring the effectiveness of triggers and customer interaction in modern marketing theory. Particular attention is paid to the integration of qualitative and quantitative approaches to assessing the ...
V. Bobrovnyk, Z. Andrushkevych
doaj   +1 more source

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