Results 81 to 90 of about 7,574,742 (332)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Reference points of corporate monetary policy
The aim of the present work is an attempt to estimate the effect of financial flexibility on the amount of cash reserves with the influence of the hypothesis of precautionary motives, in other words, to get the answer -how do companies manage liquid ...
C. I. Lutsenko
doaj
Use of GPS method in the measurement of the positional shift of a ground dam [PDF]
Because of qualitative changes in the precision of the apparatus and the methods of determination of the space position of points on the earth surface (GPS method), as well as because of the fact that in the measurement there are shifts (observed points)
Jozef Štubňa
doaj
The data collection location for this study is Longhu Tianjie, a shopping mall situated at No. 99 Wenjing Road, Jiangbei Pukou District, Nanjing, China.
Yadang Chen (16957474) +7 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The paper discusses fish stock assessment methods, emphasising methods for assessing stocks in developing nations. We present the advantages and disadvantages of each method discussed.
Francisco Chamera +5 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Promotion or Prevention Messaging?: A Field Study on What Works When You Still Have to Work
This article addresses the timely subject of the reactions toward a Sunday trade ban in Poland. The law introduced in March 2018 created a division among service employees: (1) those who used to work on Sundays before the law and now enjoy work-free ...
Marta Anna Roczniewska, E. Tory Higgins
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

