Results 131 to 140 of about 7,597,672 (301)

Bayesian Approach to Estimation of Intraclass Correlation using Reference Prior

open access: yes, 2007
For the balanced variance component model when the intraclass correlation coefficient is of interest, Bayesian analysis is often appropriate. Berger and Bernardo's (1992a) grouped ordering reference prior approach is used to analyze this model.
Younshik Chung, Dipak K. Dey
core  

Analytical derivation of the reference prior by sequential maximization of Shannon's mutual information in the multi-group parameter case

open access: yes, 2014
We provide an analytical derivation of a non-informative prior by sequential maximization of Shannon's mutual information in the multi-group parameter case assuming reasonable regularity conditions.
Bodnar, Olha,, Elster, Clemens,
core   +1 more source

Unified radar-prior-guided multimodal learning for ground-based small UAV detection

open access: yesJournal of King Saud University: Computer and Information Sciences
Detecting small unmanned aerial vehicles (UAVs) from ground-based sensors is challenging because distant targets occupy few pixels, provide weak visual cues, and are easily confused with complex backgrounds under illumination changes.
Jiangyong Mi   +5 more
doaj   +1 more source

Learning Likelihood-Free Reference Priors.

open access: yes
Simulation modeling offers a flexible approach to constructing high-fidelity synthetic representations of complex real-world systems. However, the increased complexity of such models introduces additional complications, for example when carrying out statistical inference procedures.
Bishop, N   +4 more
openaire   +2 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Spot the prior reference [PDF]

open access: yesJournal of the Staple Inn Actuarial Society, 1951
openaire   +1 more source

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