Results 101 to 110 of about 3,146,031 (302)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

They CAN and they SHOULD and it’s BOTH AND: The role of undergraduate peer mentors in the reference conversation

open access: yesIn the Library with the Lead Pipe, 2018
In Brief: Academic libraries hire and train student employees to answer reference questions which can result in high-impact employment experiences for these students. By employing students in this role, opportunities are created for peer-to-peer learning
Hailley Fargo
doaj  

Intervention design for artificial intelligence-enabled macular service implementation: a primary qualitative study

open access: yesImplementation Science Communications
Background Neovascular age-related macular degeneration (nAMD) is one of the largest single-disease contributors to hospital outpatient appointments. Challenges in finding the clinical capacity to meet this demand can lead to sight-threatening delays in ...
Henry David Jeffry Hogg   +5 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Exploring the evolution of reference services literature using Reference Publication Year Spectroscopy (RPYS) [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2018
Purpose: To identify major events in the development of Reference Services literature. Methodology: Reference Publication Year Spectroscopy (RPYS) technique is used. Initial data was obtained from the Scopus by scientometrics method.
Afshin Mousavi Chelak   +2 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Digital Reference Services: A Challenge for Reference Work and Philosophy [PDF]

open access: yes, 2005
This literature offers historical overview on the topic library reference services trying to compare it with actual trends in librarianship and with the actual user needs in the digital ...
Giraudo, Maria Agnese
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

External Trade, Tourism and Economic Integration in Latin America [PDF]

open access: yes
We analyse the positive effects of industry, external trade and tourism on economic development, with a comparative study of twenty-two Latin American countries and an especial reference to the case of MERCOSUR and Andean Community.
Aguayo, Eva   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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