Results 111 to 120 of about 3,146,031 (302)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
TINA as a virtual market place for telecommunication and information services: the VITAL experiment
, 1999 The VITAL (Validation of Integrated Telecommunication Architectures for the Long-Term) project has defined, implemented and demonstrated an open distributed telecommunication architecture (ODTA) for deploying, managing and using a set of heterogeneous ...
Canal, Gianni +4 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Liberalisation of International Trade in Financial Services in Southeast Asia: Indonesia, Malaysia, Philippines and Thailand [PDF]
This paper outlines the analytical rationale in favour of liberalisation of trade in services with particular reference to the key infrastrucutural sub-sectors of financial services and discusses the empirical evidence thereof. The paper goes on to offer
Rahul Sen, Ramkishen Rajan
core
The Open University Library in your pocket [PDF]
, 2010 The Open University library is working to support mobile learners through provision of mobile access to information management skills tutorials, the library website, and the library helpdesk. In 2007, we joined hands with the Athabasca University library
Mills, Keren, Sheikh, Hassan
core
Annotated Bibliography: The Reference Desk: Grand Idea or Gone Down the River?
, 2018 This bibliography is from a panel presentation at the 2017 ACL Conference. The goal of this panel was to explore different rationales or sets of values that illustrated the continuation of the reference desk and reference service as essential to the ...
Jones, Alison +3 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Video Reference: A Pre-Test and Pilot Project [PDF]
, 2010 Hennepin County Library will open two new, larger libraries without the ability to increase FTE. We are developing a pilot plan to see if a video service can address the need to provide reference service in a busy library as part of an overall staffing ...
Clifford, Christine, Nelson, Jennifer
core +1 more source