Results 41 to 50 of about 744,128 (306)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Library of Parliament’s Competency-Based New-Librarian Development Program
Partnership: The Canadian Journal of Library and Information Practice and Research, 2023 Employee orientation and development are essential organizational processes. This paper examines a competency-based new-librarian development program in a legislative library setting, emphasizing program redesign and continuous improvement.
Melissa Fraser-Arnott, Maureen Martyn
doaj +1 more source
The impact of the Internet on Reference services in Higher Education libraries in South Africa [PDF]
, 2002 Internet access has become an indicator of a country’s socio-economic status in the Information Society. Libraries of higher education institutions support the parent institutions’ objective to produce graduates able to function in this society ...
Darries, Fatima
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
IFLA Digital Reference Guidelines
, 2011 The purpose of these guidelines is to promote digital reference best practices on an international basis. The online environment is uniquely suited to consortial models of work and to the development of shared resources.
IFLA Reference and Information Services Section
core +3 more sources
Bilgi Dünyası, 2016 The roving reference concept is relatively new in the Philippines. In 2012, the De La Salle University (DLSU) Libraries shared in its OCLC report entitled “Reference and Information Services in Selected Philippine Academic Libraries: Trends and ...
Joseph Marmol Yap, May Laureno Cajes
doaj +3 more sources
Studying the status of Shahid Chamran University libraries and information services [PDF]
بازیابی دانش و نظامهای معنایی, 2015 purpose: This study examined the status of service delivery in the collection Shahid Chamran University libraries, including school libraries and the central library.
Mohammad Hassan Azimi
doaj
Harm Reduction Journal, 2018 Background People who inject drugs (PWID) are at an increased risk of wound botulism, a potentially fatal acute paralytic illness. During the first 6 months of 2015, a large outbreak of wound botulism was confirmed among PWID in Scotland, which resulted ...
Kirsten M. A. Trayner +7 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Synoptic Reference: Introducing a Polymathic Approach to Reference Services [PDF]
Library Trends, 2015 Studies show that reaching beyond disciplinary boundaries can be an effective method for understanding complex research problems and enriching student learning. However, despite the increased attention given to interdisciplinary thinking in higher education, there is much that remains to be understood about the growing centrality of interdisciplinary ...
Scimeca, Ross, Labaree, Robert V.
openaire +2 more sources