Results 71 to 80 of about 3,126,236 (305)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Library performance measurement in the digital age [PDF]
, 2011 Book synopsis: University libraries around the world have embraced the possibilities of the digital learning environment, facilitating its use and proactively seeking to develop the provision of electronic resources and services.
Conyers, A., Payne, Philip
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Winnowing ontologies based on application use [PDF]
, 2006 The requirements of specific applications and services are often over estimated when ontologies are reused or built. This sometimes results in many ontologies being too large for their intended purposes.
A. Magkanaraki +12 more
core +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Selective Dissemination of Journals Information and its Effect on Citation Indicators
پیاورد سلامت, 2021 Background and Aim: In this study, in order to increase the visibility of articles in Scopus journals of Tehran University of Medical Sciences (TUMS), selective dissemination of information (SDI) service was presented and its impact on some citation ...
Marjan Ghazi-Saeedi +2 more
doaj
Ethical Aspects of Insurance [PDF]
, 1972 The nature and ethical basis for insurance in general will be briefly discussed. Reference will then be made to alternatives to insurance as a means for meeting the cost of medical care.
Buckley, Louis F.
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Academic digital library in Malaysia: A case study on the status of digital reference services [PDF]
, 2010 This paper highlights the current status of digital library services provided by selected public academic libraries in Malaysia. The drift from traditional library to digital library architecture has set drastic changes in favor of adopting knowledge ...
Abdul Kadir, Razilan +1 more
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