Results 191 to 200 of about 15,390,687 (342)

Analytical performance of commercial myositis-specific autoantibody tests evaluated against immunoprecipitation assays as a reference standard: A systematic review and meta-analysis. [PDF]

Semin Arthritis Rheum
Gono T, Gil-Vila A, Selva-O'Callaghan A, van Royen-Kerkhof A, Vincze A, Mecoli C, Gómez-Martín D, Hamann D, Conticini E, Griger Z, Torres-Ruiz JJ, Pauling JD, Chinoy H, Gupta L, Bodoki L, Nasir N, Chavan PP, Khubchandani R, Ernesto TA, Hamaguchi Y, Rider LG, Aggarwal R, Tansley S, Rönnelid J, Kuwana M, McHugh NJ, International Myositis Assessment and Clinical Studies Group (IMACS) Myositis Autoantibody Scientific Interest Group (SIG) Study.   +26 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Reference standards.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979
G, Myers, J, Quirk, V, Poplak
openaire   +1 more source

Comparison of <i>Acinetobacter calcoaceticus-baumannii</i> Complex Identification by MALDI-TOF Mass Spectrometry and Biochemical Method, Using Whole‑genome Sequencing as the Reference Standard. [PDF]

Infect Drug Resist
Prakika A, Srisai P, Nithimongkolchai N, Khongmee A, Manbenmad V, Hongsa C, Kuwatjanakul W, Wonglakorn L, Kewcharoenwong C, Lertmemongkolchai G, Faksri K, Nithichanon A.   +11 more
europepmc   +1 more source

Interrater agreement of multi-professional case review as reference standard for specialist palliative care need: a mixed-methods study. [PDF]

BMC Palliat Care, 2023
Müller E, Müller MJ, Seibel K, Boehlke C, Schäfer H, Klein C, Heckel M, Simon ST, Becker G.   +8 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

MRI of wrist ligament trauma was similar at 7 T and 3 T with arthroscopy as a reference standard. [PDF]

Eur Radiol
Götestrand S, Flondell M, Lundin B, Aksyuk E, Shalhoub RA, Szaro P, Hedström E, Björkman A, Geijer M.   +8 more
europepmc   +1 more source

A Reference Standard for Analytical Testing of Erythropoietin. [PDF]

Pharm Res, 2022
Tu H, Carrick K, Potts R, Hasselberg M, Verdecia M, Burns C, Cowper B, Atouf F.   +7 more
europepmc   +1 more source

Fuzzy gold standards: Approaches to handling an imperfect reference standard.

E -journal of dentistry, 2018
T. Walsh
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source