Results 1 to 10 of about 514,099 (251)

Update on Non-Interchangeability of Botulinum Neurotoxin Products

Toxins
The growing use of botulinum neurotoxins (BoNTs) for medical and aesthetic purposes has led to the development and marketing of an increasing number of BoNT products.
Mitchell F. Brin, Mariana Nelson, Nazanin Ashourian, Amy Brideau-Andersen, John Maltman   +4 more
doaj   +1 more source

Shades of the Rainbow Serpent? A KhoeSan Animal between Myth and Landscape in Southern Africa—Ethnographic Contextualisations of Rock Art Representations

Arts, 2014
The snake is a potent entity in many cultures across the world, and is a noticeable global theme in rock art and inscribed landscapes. We mobilise our long-term ethnographic research with southern African KhoeSan peoples to situate and interpret the ...
Sian Sullivan, Chris Low
doaj   +1 more source

Comparative Analyses of Antiviral Potencies of Second-Generation Integrase Strand Transfer Inhibitors (INSTIs) and the Developmental Compound 4d Against a Panel of Integrase Quadruple Mutants

Viruses
Second-generation integrase strand transfer inhibitors (INSTIs) are strongly recommended for people living with HIV-1 (PLWH). The emergence of resistance to second-generation INSTIs has been infrequent and has not yet been a major issue in high-income ...
Steven J. Smith, Xue Zhi Zhao, Stephen H. Hughes, Terrence R. Burke   +3 more
doaj   +1 more source

Neutralizing antibody landscape of the non-polio Enteroviruses and future strategy

Frontiers in Immunology
The non-polio Enteroviruses (NPEVs), consist of enteroviruses, coxsackieviruses, echoviruses, and rhinoviruses, are causative agents for a wide variety of diseases, ranging from common cold to encephalitis and acute flaccid paralysis (AFP).
Hongye Wang, Wenbing Zhu, Ya Li, Ming Sun   +3 more
doaj   +1 more source

Enhanced Anti-Babesia Efficacy of Buparvaquone and Imidocarb When Combined with ELQ-316 In Vitro Culture of Babesia bigemina

Pharmaceuticals
Background/Objectives: B. bigemina is a highly pathogenic and widely distributed tick-borne disease parasite responsible for bovine babesiosis. The development of effective and safe therapies is urgently needed for global disease control. The aim of this
Natalia M. Cardillo, Nicolas F. Villarino, Paul A. Lacy, Joseph S. Doggett, Michael K. Riscoe, Carlos E. Suarez, Massaro W. Ueti, Chungwon J. Chung   +7 more
doaj   +1 more source

Producing high-quantity and high-quality recombinant adeno-associated virus by low-cis triple transfection

Molecular Therapy: Methods & Clinical Development
Recombinant adeno-associated virus (rAAV)-based gene therapy is entering clinical and commercial stages at an unprecedented pace. Triple transfection of HEK293 cells is currently the most widely used platform for rAAV manufacturing.
Hao Liu, Yue Zhang, Mitchell Yip, Lingzhi Ren, Jialing Liang, Xiupeng Chen, Nan Liu, Ailing Du, Jiaming Wang, Hao Chang, Hyejin Oh, Chen Zhou, Ruxiao Xing, Mengyao Xu, Peiyi Guo, Dominic Gessler, Jun Xie, Phillip W.L. Tai, Guangping Gao, Dan Wang   +19 more
doaj   +1 more source

Limited Potential or Unfavorable Manipulations? Strategies Toward Efficient Mesenchymal Stem/Stromal Cell Applications

Frontiers in Cell and Developmental Biology, 2020
Despite almost 50 years of research and over 20 years of preclinical and clinical studies, the question of curative potential of mesenchymal stem/stromal cells (MSCs) is still widely discussed in the scientific community.
Antonina Lavrentieva, Andrea Hoffmann, Cornelia Lee-Thedieck   +2 more
doaj   +1 more source

Distribution and the potential growth of ganitri ( Elaeocarpus ganitrus Roxb ) in Central Java

Jurnal Ilmu Kehutanan, 2014
Ganitri (Elaeocarpus ganitrus Roxb) is a multi-purpose species that has the potential to be developed. This species has been known and cultivated by people, particularly in the region of Central Java.
Asep Rohandi, Gunawan Gunawan
doaj   +1 more source

Role of testosterone in men with erectile dysfunction

International Journal of Medicine and Health Development, 2000
The present study was carried out to determine the effect of testosterone therapy on Erectile dysfunction (ED) patients with normal and low testosterone levels.
Aloy E Aghaji
doaj  

Polyene-Based Derivatives with Antifungal Activities

Pharmaceutics
Polyenes are a class of organic compounds well known for their potent antifungal properties. They are effective due to their ability to target and disrupt fungal cell membranes by binding to ergosterol and forming pores.
Kwanele Ngece, Thabisa L. Ntondini, Vuyolwethu Khwaza, Athandwe M. Paca, Blessing A. Aderibigbe   +4 more
doaj   +1 more source