Results 1 to 10 of about 1,109,767 (188)
Safety Evaluation of Cosmetic Ingredients Regarding Their Skin Sensitization Potential
Cosmetics, 2016 Up to today, product safety evaluation in the EU is predominantly based on data/information on their individual ingredients. Consequently, the quality and reliability of individual ingredient data is of vital interest.
Winfried Steiling
doaj +2 more sources
Evaluation of dermal irritation and skin sensitization due to vitacoxib
Toxicology Reports, 2017 The prediction of side-effects is a key issue in the REACH initiative on chemicals in the preclinical testing of drugs. The dermal irritation and skin sensitization toxicity potential of a new molecule, vitacoxib, were invested in rabbits and guinea pigs
Jianzhong Wang +7 more
doaj +2 more sources
International Journal of Women's Dermatology, 2020 The prevention of allergic contact dermatitis hinges on maintaining the integrity of the skin barrier and responding appropriately when it is disturbed. Although intact skin is subject to sensitization via highly irritating allergens, such as poison ivy,
Susan Nedorost, MD, Margaret Hammond, MD
doaj +1 more source
Indian Journal of Dermatology, Venereology, and Leprology, 2013 Sensitive skin is less tolerant to frequent and prolonged use of cosmetics and toiletries. It is self-diagnosed and typically unaccompanied by any obvious physical signs of irritation. With the change in lifestyle and also with increased opportunity to use many new brands of cosmetics and toiletries, there has been an increase in females complaining of
Arun C, Inamadar, Aparna, Palit
openaire +2 more sources
Journal of Immunotoxicology, 2018 Skin sensitization is an important occupational health problem and immunotoxicity endpoint. Considering animal welfare and time and cost savings, many alternative approaches, such as those conducted in vitro, in silico, and in chemo, have been proposed ...
Weicheng Zhang, Libao Chen, Lunguang Yao
doaj +1 more source
Analysis of publically available skin sensitization data from REACH registrations 2008-2014
ALTEX: Alternatives to Animal Experimentation, 2016 The public data on skin sensitization from REACH registrations already included 19,111 studies on skin sensitization in December 2014, making it the largest repository of such data so far (1,470 substances with mouse LLNA, 2,787 with GPMT, 762 with both
Thomas Luechtefeld +5 more
doaj +1 more source
Scientific Reports, 2022 The only official method that can detect the skin sensitizing potential of chemicals, including the elicitation response, is the OECD test guideline (TG) 406. However, this guideline uses guinea pigs, which requires complex procedures. Since a simple and
Ryo Kamata +5 more
doaj +1 more source
Research Progress on Alternative Methods of Skin Sensitization Test
Shiyan dongwu yu bijiao yixue, 2022 Allergic contact dermatitis is a type Ⅳ hypersensitivity reaction caused by repeated skin exposure to a substance and is a common public health problem. Traditional skin sensitization tests are based on animal experiments such as guinea pig maximum test ...
HUANG Jingyi +4 more
doaj +1 more source
The Prevalence of Sensitive Skin [PDF]
Frontiers in Medicine, 2019 Sensitive skin has been described as unpleasant sensory responses to stimuli that should not provoke such sensations. Objectively measurable signs of irritation are not always present in individuals with sensitive skin, however, subjective sensory effects such as, itching, burning, stinging, tightness, and dryness, are consistently present.
openaire +3 more sources
Zhongguo yiliao qixie zazhiTests for skin sensitization are commonly used methods for evaluating the sensitization of medical devices. With the development of animal welfare and scientific technology, various toxicology evaluation tools such as in vitro experiments and non-testing
Likui SUN +4 more
doaj +1 more source