Results 41 to 50 of about 1,109,767 (188)

The role of skin inflammation, barrier dysfunction, and oral tolerance in skin sensitization to gluten-derived hydrolysates in a rat model. [PDF]

Contact Dermatitis, 2023
Background: Adverse reactions to wheat-containing skin care products have been linked to food allergy development.Objectives: To determine the role of skin barrier dysfunction and inflammation in sensitization to gluten-derived hydrolysates via the skin ...
Larsen JM, Ballegaard AR, Dominguez AS, Kristoffersen NJ, Maryniak NZ, Locke AV, Kazemi S, Epstein M, Madsen CB, Bøgh KL.   +9 more
europepmc   +2 more sources

Skin exposure promotes a Th2-dependent sensitization to peanut allergens [PDF]

, 2014
Sensitization to foods often occurs in infancy, without a known prior oral exposure, suggesting that alternative exposure routes contribute to food allergy.
Maleki, Soheila J., Soheila J. Maleki, Hugh A. Sampson, Galina Grishina, Benedé, Sara, Sampson, Hugh A., Goswami, Ritobrata, M. Cecilia Berin, Dunkin, David, Sara Benedé, David Dunkin, Kirsi M. Järvinen, Tordesillas, Leticia, Leticia Tordesillas, Ritobrata Goswami, Grishina, Galina, Järvinen, Kirsi M., Berin, M. Cecilia   +17 more
core   +1 more source

Evaluation of skin sensitization based on interleukin‑2 promoter activation in Jurkat cells [PDF]

, 2021
Skin sensitization is an allergic reaction caused by certain chemical substances, and is an important factor to be taken into consideration when evaluating the safety of numerous types of products.
Satoh, Ayano, Nagahata, Taichi, Takayama, Eiji, Hikasa, Haruka, Tsujino, Yoshio, Taichi Nagahata, Yoshio Tsujino, Ayano Satoh, Eiji Takayama, Haruka Hikasa   +9 more
core   +1 more source

Is There a Need for Repetition of Skin Test in Childhood Allergic Diseases? Repetition of Skin Test and Allergic Diseases

Allergology International, 2014
Background: Skin prick tests are widely used to determine sensitivity in allergic diseases. There is limited information about the natural history of skin sensitization tests and factors that affect them.
Mahmut Dogru, Ilknur Bostanci, Serap Ozmen, Tayfur Ginis, Handan Duman   +4 more
doaj   +1 more source

Differential susceptibility between skin and vaginal mucosa in sensitization phase of allergic contact dermatitis in mice

Immunity, Inflammation and Disease, 2020
Introduction Mechanisms underlying skin sensitization in allergic contact dermatitis have been actively studied using the murine contact hypersensitivity (CHS) model. However, much less is known about sensitization at the vaginal mucosa (VM).
Taku Nishijo, Kanako Nakayama, Masaaki Miyazawa, Yasutaka Kuroda, Hitoshi Sakaguchi   +4 more
doaj   +1 more source

The Sensitive Skin Syndrome

Indian Journal of Dermatology, 2012
Sensitive skin syndrome (SSS) is a common and challenging condition, yet little is known about its underlying pathophysiology. Patients with SSS often present with subjective complaints of severe facial irritation, burning, and/or stinging after application of cosmetic products. These complaints are out of proportion to the objective clinical findings.
Hadar Lev-Tov, Howard I Maibach
openaire   +3 more sources

Evaluation of the Skin Sensitization Potential of Carbon Nanotubes Using Alternative In Vitro and In Vivo Assays

Toxics, 2020
Carbon nanotubes (CNTs) are one of the major types of nanomaterials that have various industrial and biomedical applications. However, there is a risk of accidental exposure to CNTs in individuals involved in their large-scale production and in ...
Sung-Hyun Kim, Dong Han Lee, Jin Hee Lee, Jun-Young Yang, Hyo-Sook Shin, JeongPyo Lee, Kikyung Jung, Jayoung Jeong, Jae-Ho Oh, Jong Kwon Lee   +9 more
doaj   +1 more source

Proteolytic activity accelerates the TH17/TH22 recall response to an epicutaneous protein allergen-induced TH2 response

Journal of Immunotoxicology, 2022
Epicutaneous exposure to protein allergens, such as papain, house dust mite (HDM), and ovalbumin (OVA), represents an important mode of sensitization for skin diseases including protein contact dermatitis, immunologic contact urticaria, and atopic ...
Akira Ogasawara, Takuo Yuki, Asuka Katagiri, Yi-Ting Lai, Yutaka Takahashi, David Basketter, Hitoshi Sakaguchi   +6 more
doaj   +1 more source

Skin sensitization in silico protocol [PDF]

, 2020
The assessment of skin sensitization has evolved over the past few years to include in vitro assessments of key events along the adverse outcome pathway and opportunistically capitalize on the strengths of in silico methods to support a weight of ...
Zwickl, Craig, Milchak, Lawrence, Paulino, Ana Theresa, Cronini, Mark T. D., Roberts, David W., Tice, RR, Neilson, Louise, Hardy, B, Mestres, Jordi, Bercu, Joel, Anger, LT, Magby, J, Fearon, Ian M., Crooks, I, Campbell, Sarah, Weiler, Thibaud, Wichard, J, Suarez-Rodrigez, Diana, Neilson, L, Mestres i López, Jordi, Wichard, Joerg, Szabo, DT, Bobst, Sol, Woolley, D, Miller, Scott, Jolly, R, Myatt,Glenn J., Weiler, T, Fearon, IM, Gervais, V, Vuorinen, Anna, Parris, P, Lomnitski, Liat, Doktorova, Tatyana, Milchak, L, Beilke, Lisa, Cross, Kevin P., Campbell, S, Bobst, S, Faulkner, D, Zwickl, C, Fehr, Markus, Stidl, Reinhard, Magby, Jason, Exner, T, Krupp, Eckart, Paulino, Alexandre, Schlecker, H, Parakhia, Rahul, Schlecker, Harald, Faulkner, David, Glowienke, S, Whritenour, J, Glowienke, Susanne, Bercu, J, Vuorinen, A, Hardy, Barry, Lomnitski, L, Myatt, GJ, Cronin, MTD, Exner, Thomas, Gad, Shayne C., Parris, Patricia, Brigo, A, Hasselgren, C, Ahlberg, E, Gad, SC, Johnson, Candice, Crooks, Ian, Roberts, DW, Hillegass, J, Urbisch, D, Urbisch, Daniel, Wall, Brian, Cross, CP, Fehr, M, Bower, D, Muster, W, Johnson, C, Parenty, A, Parakhia, R, Brigo, Alessandro, Giddings, Amanda, Benigni, R, Muster, Wolfgang, Krupp, E, Benigni, Romualdo, Wall, B, Suarez-Rodrigez, D, Tice, Raymond R., Hillegass, Jedd, Paulino, AT, Bower, David, Szabo, David T., Mestres, J, Paulino, A, Ahlberg, Ernst, Whritenour, Jessica, Gervais, Veronique, Hasselgren, Catrin, Giddings, A, Parentys, Alexis, Woolley, David, Jolly, Robert, Anger, Lennart T., White, Angela T., White, AT, Doktorova, T, Miller, S, Myatt, Glenn J., Stidl, R, Beilke, L, Bower, David,, Wichard, Joerg,, Tice, Raymond R.,, Wall, Brian,, Cronini, Mark T. D.,, Bobst, Sol,, Exner, Thomas,, Crooks, Ian,, Neilson, Louise,, Paulino, Alexandre,, Anger, Lennart T.,, Myatt, Glenn J.,, Zwickl, Craig,, Whritenour, Jessica,, Bercu, Joel,, Cross, Kevin P.,, Weiler, Thibaud,, Krupp, Eckart,, Johnson, Candice,, Lomnitski, Liat,, Jolly, Robert,, Gad, Shayne C.,, Suarez-Rodrigez, Diana,, Benigni, Romualdo,, Magby, Jason,, Gervais, Veronique,, Roberts, David W.,, Faulkner, David,, Stidl, Reinhard,, Hardy, Barry,, Szabo, David T.,, Giddings, Amanda,, Parentys, Alexis,, Brigo, Alessandro,, Parris, Patricia,, Mestres, Jordi,, Woolley, David,, Fearon, Ian M.,, Miller, Scott,, Urbisch, Daniel,, Paulino, Ana Theresa,, Schlecker, Harald,, Hillegass, Jedd,, Hasselgren, Catrin,, Parakhia, Rahul,, Doktorova, Tatyana,, Milchak, Lawrence,, Beilke, Lisa,, Campbell, Sarah,, Fehr, Markus,, Glowienke, Susanne,, Muster, Wolfgang,, White, Angela T.,, Ahlberg, Ernst,, Vuorinen, Anna,   +166 more
core   +1 more source

Anti-hapten antibodies in response to skin sensitization.

, 2015
Whereas T lymphocyte (T cell) activation is the key event in the acquisition of skin sensitization and subsequent elicitation of allergic contact dermatitis, the humoral component of immune responses to organic contact allergens has received little ...
Helen Singleton, Gavin Maxwell, Williams, Jason, Kimber, Ian, Jason Williams, Maxwell, Gavin, Gellatly, Nichola, Ian Kimber, Rebecca J. Dearman, Amy Popple, Singleton, Helen, Popple, Amy, Dearman, Rebecca J, Nichola Gellatly, Friedmann, Peter S, Peter S. Friedmann   +15 more
core   +2 more sources