Results 41 to 50 of about 69,829 (286)

Sensitization of Guinea Pig Skin to Imported Fire Ant Alkaloids and Establishment of an Inflammatory Model

, 2023
Imported fire ants (IFAs), Solenopsis invicta, release their venom through multiple stings that induce inflammation, allergies, shock, and even death. Although IFA venom protein sensitization and related subcutaneous immunotherapy have been studied, few ...
Juan Zhang, Jun Huang, Xiaowei Li, Yipeng Xu, Yueze Liu, Yaobin Lu   +5 more
core   +1 more source

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention [PDF]

, 2014
BackgroundAtopic dermatitis (atopic eczema) is a chronic inflammatory skin disease that has reached epidemic proportions in children worldwide and is increasing in prevalence.
Cork, Michael J., Chen, Zunqiu, Simpson, Eric L., Chalmers, Joanne R., Hanifin, Jon M., Thomas, Kim S., McLean, W. H. Irwin, Chen, Yiyi, Williams, Hywel C., Brown, Sara J., McLean, W.H. Irwin, Irwin McLean, W.H.   +11 more
core   +1 more source

Is There a Need for Repetition of Skin Test in Childhood Allergic Diseases? Repetition of Skin Test and Allergic Diseases

Allergology International, 2014
Background: Skin prick tests are widely used to determine sensitivity in allergic diseases. There is limited information about the natural history of skin sensitization tests and factors that affect them.
Mahmut Dogru, Ilknur Bostanci, Serap Ozmen, Tayfur Ginis, Handan Duman   +4 more
doaj   +1 more source

Differential susceptibility between skin and vaginal mucosa in sensitization phase of allergic contact dermatitis in mice

Immunity, Inflammation and Disease, 2020
Introduction Mechanisms underlying skin sensitization in allergic contact dermatitis have been actively studied using the murine contact hypersensitivity (CHS) model. However, much less is known about sensitization at the vaginal mucosa (VM).
Taku Nishijo, Kanako Nakayama, Masaaki Miyazawa, Yasutaka Kuroda, Hitoshi Sakaguchi   +4 more
doaj   +1 more source

Effects of geohelminth infection and age on the associations between allergen-specific IgE, skin test reactivity and wheeze: a case-control study. [PDF]

, 2013
BACKGROUND: Most childhood asthma in poor populations in Latin America is not associated with aeroallergen sensitization, an observation that could be explained by the attenuation of atopy by chronic helminth infections or effects of age.
Oviedo, G, Platts-Mills, TA, Vaca, M., Workman, L. J., Platts-Mills, T. A. E., Barreto, M. L., Rodrigues, LC, Moncayo, A-L, Workman, LJ, Vaca, M, Chico, ME, Platts-Mills, TAE, Oviedo, G., Barreto, ML, Moncayo, AL, Rodrigues, L. C., Chico, M. E., Cooper, PJ, Cooper, Philip, Moncayo, A.-L.   +19 more
core   +1 more source

Development Status and Evaluation Strategy Considerations on In Vitro Alternative Methods for Skin Sensitization Testing of Medical Devices

Zhongguo yiliao qixie zazhi
Tests for skin sensitization are commonly used methods for evaluating the sensitization of medical devices. With the development of animal welfare and scientific technology, various toxicology evaluation tools such as in vitro experiments and non-testing
Likui SUN, Xiaoxia SUN, Xiaofei WANG, Chenghu LIU, Min WAN   +4 more
doaj   +1 more source

A comprehensive review of the Direct Peptide Reactivity Assay in skin sensitization testing: Applicability, limitations, and considerations [PDF]

Arhiv za farmaciju
Skin sensitization is a crucial endpoint in the safety assessment of chemicals, with the Direct Peptide Reactivity Assay (DPRA) emerging as a valuable in chemico method for evaluating a substance's sensitization potential.
Omeragić Elma, Imamović Belma, Dedić Mirza, Mujezin Indira, Bečić Ervina   +4 more
doaj   +1 more source

The Sensitive Skin Syndrome

Indian Journal of Dermatology, 2012
Sensitive skin syndrome (SSS) is a common and challenging condition, yet little is known about its underlying pathophysiology. Patients with SSS often present with subjective complaints of severe facial irritation, burning, and/or stinging after application of cosmetic products. These complaints are out of proportion to the objective clinical findings.
Hadar Lev-Tov, Howard I Maibach
openaire   +3 more sources

Evaluation of the Skin Sensitization Potential of Carbon Nanotubes Using Alternative In Vitro and In Vivo Assays

Toxics, 2020
Carbon nanotubes (CNTs) are one of the major types of nanomaterials that have various industrial and biomedical applications. However, there is a risk of accidental exposure to CNTs in individuals involved in their large-scale production and in ...
Sung-Hyun Kim, Dong Han Lee, Jin Hee Lee, Jun-Young Yang, Hyo-Sook Shin, JeongPyo Lee, Kikyung Jung, Jayoung Jeong, Jae-Ho Oh, Jong Kwon Lee   +9 more
doaj   +1 more source

Proteolytic activity accelerates the TH17/TH22 recall response to an epicutaneous protein allergen-induced TH2 response

Journal of Immunotoxicology, 2022
Epicutaneous exposure to protein allergens, such as papain, house dust mite (HDM), and ovalbumin (OVA), represents an important mode of sensitization for skin diseases including protein contact dermatitis, immunologic contact urticaria, and atopic ...
Akira Ogasawara, Takuo Yuki, Asuka Katagiri, Yi-Ting Lai, Yutaka Takahashi, David Basketter, Hitoshi Sakaguchi   +6 more
doaj   +1 more source