Results 21 to 30 of about 1,109,767 (188)
Mechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity
, 1993 Twenty organic Salmonella mutagens, seven of which (including benzo[a]pyrene) are established skin carcinogens, and one of which (2-chloroethanol) is a well-defined noncarcinogen to skin, have been evaluated for skin-sensitizing activity using the local ...
R D Callander +9 more
core +10 more sources
Skin Sensitization Testing Using New Approach Methodologies. [PDF]
ToxicsSkin sensitization, representing one of the regulatory toxicity endpoints, is seeing significant progress in the uptake of new approach methodologies, comprising non-animal evaluations, to provide regulatory and product development information on ...
Strickland J.
europepmc +3 more sources
Applied Sciences, 2022 Background: Shellfish allergy is one of the most common food allergies. Recent studies have shown that sensitization to allergens via the skin is involved in the development of food allergies.
Mayuko Ichimura-Shimizu +14 more
doaj +1 more source
Evaluation of the global performance of eight in silico skin sensitization models using human data
ALTEX: Alternatives to Animal Experimentation, 2021 Allergic contact dermatitis, or the clinical manifestation of skin sensitization, is a leading occupational hazard. Several testing approaches exist to assess skin sensitization, but in silico models are perhaps the most advantageous due to their high ...
Emily Golden +5 more
doaj +1 more source
Journal of the European Academy of Dermatology and Venereology, 2016 AbstractSensitive skin is a clinical condition defined by the self‐reported facial presence of different sensory perceptions, including tightness, stinging, burning, tingling, pain and pruritus. Sensitive skin may occur in individuals with normal skin, with skin barrier disturbance, or as a part of the symptoms associated with facial dermatoses such as
L, Misery, K, Loser, S, Ständer
openaire +2 more sources
PreSS/MD: Predictor of Skin Sensitization Caused by Chemicals Leaching from Medical Devices [PDF]
, 2022 Safety evaluation for medical devices includes the toxicity assessment of chemicals used in device manufacturing, cleansing and/or sterilization that may leach into a patient.
Joyce, Borba +8 more
core +1 more source
Skin Sensitization Potential and Cellular ROS-Induced Cytotoxicity of Silica Nanoparticles
Nanomaterials, 2021 Nowadays, various industries using nanomaterials are growing rapidly, and in particular, as the commercialization and use of nanomaterials increase in the cosmetic field, the possibility of exposure of nanomaterials to the skin of product producers and ...
Sung-Hyun Kim +7 more
doaj +1 more source
A QSAR classification model of skin sensitization potential based on improving binary crow search algorithm [PDF]
, 2020 Classifying of skin sensitization using the quantitative structure-activityrelationship (QSAR) model is important. Applying descriptor selection isessential to improve the performance of the classification task.
Algamal, Zakariya Yahya; University of Mosul +1 more
core +1 more source
Frontiers in Allergy, 2021 Neonatal mice with heterozygous mutations in genes encoding the skin barrier proteins filaggrin and mattrin (flaky tail mice [FT+/−]) exhibit oral peanut-induced anaphylaxis after skin sensitization.
Lauren M. Buelow +5 more
doaj +1 more source
Sensitive skin: an overview [PDF]
International Journal of Cosmetic Science, 2012 SynopsisSensitive skin is a condition of subjective cutaneous hyper‐reactivity to environmental factors. Subjects experiencing this condition report exaggerated reactions when their skin is in contact with cosmetics, soaps and sun screens, and they often report worsening after exposure to dry and cold climate. Although no sign of irritation is commonly
E, Berardesca, M, Farage, H, Maibach
openaire +2 more sources