Results 21 to 30 of about 783,846 (314)

Frequency and Severity of Neutropenia Associated with Food and Drug Administration Approved and Compounded Formulations of Lomustine in Dogs with Cancer. [PDF]

open access: yes, 2015
BackgroundCompounded lomustine is used commonly in veterinary patients. However, the potential variability in these formulations is unknown and concern exists that compounded formulations of drugs may differ in potency from Food and Drug Administration ...
Burton, JH   +5 more
core   +2 more sources

Development and Qualification of an Antigen Integrity Assay for a Plasmodium falciparum Malaria Transmission Blocking Vaccine Candidate, Pfs230

open access: yesVaccines, 2022
During development of a subunit vaccine, monitoring integrity of the recombinant protein for process development and quality control is critical. Pfs230 is a leading malaria transmission blocking vaccine candidate and the first to reach a Phase 2 ...
Kazutoyo Miura   +9 more
doaj   +1 more source

Anti-cancer effects and mechanism of actions of aspirin analogues in the treatment of glioma cancer [PDF]

open access: yes, 2012
INTRODUCTION: In the past 25 years only modest advancements in glioma treatment have been made, with patient prognosis and median survival time following diagnosis only increasing from 3 to 7 months.
A. A. Hill   +312 more
core   +1 more source

Distribution and the potential growth of ganitri ( Elaeocarpus ganitrus Roxb ) in Central Java

open access: yesJurnal Ilmu Kehutanan, 2014
Ganitri (Elaeocarpus ganitrus Roxb) is a multi-purpose species that has the potential to be developed. This species has been known and cultivated by people, particularly in the region of Central Java.
Asep Rohandi, Gunawan Gunawan
doaj   +1 more source

Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Different approaches are used in the production of recombinant adeno-associated virus (rAAV). The two leading approaches are transiently transfected human HEK293 cells and live baculovirus infection of Spodoptera frugiperda (Sf9) insect cells ...
Neil G. Rumachik   +12 more
doaj   +1 more source

Anticancer metallohelices: nanomolar potency and high selectivity [PDF]

open access: yes, 2015
A range of new helicate-like architectures have been prepared via highly diastereoselective self-assembly using readily accessible starting materials. Six pairs of enantiomers [Fe2L3]Cl4.nH2O (L = various bidentate ditopic ligands NN–NN) show very good ...
Allison   +46 more
core   +1 more source

Potency, Safety, and Pharmacokinetic Profiles of Potential Inhibitors Targeting SARS-CoV-2 Main Protease

open access: yesFrontiers in Pharmacology, 2021
Effective, safe, and pharmacokinetically suitable drugs are urgently needed to curb the ongoing COVID-19 pandemic. The main protease or 3C-like protease (Mpro or 3CLpro) of SARS-CoV-2 is considered an important target to formulate potent drugs ...
Hylemariam Mihiretie Mengist   +9 more
doaj   +1 more source

Human urinary mutagenicity after wood smoke exposure during traditional temazcal use. [PDF]

open access: yes, 2014
In Central America, the traditional temazcales or wood-fired steam baths, commonly used by many Native American populations, are often heated by wood fires with little ventilation, and this use results in high wood smoke exposure.
HOLLAND, Nina   +8 more
core   +3 more sources

Ichthyofauna of Merbau River, Leuser Ecosystem Area, Indonesia: species composition, diversity, biometric condition, potency, and conservation status

open access: yesThe European Zoological Journal, 2023
The Leuser Ecosystem Area (LEA) is one of the largest conservation areas in Southeast Asia. However, the explorations of ichthyofauna at LEA are still relatively scarce compared to other vertebrates fauna.
M. Hidayat   +6 more
doaj   +1 more source

Sensor potency of the moonlighting enzyme-decorated cytoskeleton [PDF]

open access: yes, 2013
Background: There is extensive evidence for the interaction of metabolic enzymes with the eukaryotic cytoskeleton. The significance of these interactions is far from clear.
Amar Patrick   +5 more
core   +4 more sources

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