Evaluation of Nutri-Score and NewTools-score in a Norwegian setting using a reference standard based on nutrition experts' ranking of foods' healthiness. [PDF]
Paulsen MM +4 more
europepmc +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Diagnostic Accuracy and Concordance of Standardized vs. Non-Standardized Joint Physical Examination for Assessing Disease Activity in Rheumatoid Arthritis: A Paired Comparison Using Ultrasound as Reference Standard. [PDF]
Medina YF, Rondón MA.
europepmc +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Coronary computed tomography angiography is the new reference standard for the diagnosis of coronary artery disease: pros and cons. [PDF]
Dewey M +3 more
europepmc +1 more source
M. Nogueira-Barbosa +6 more
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Development of a Reference Standard to Assign Bacterial Versus Viral Infection Etiology Using an All-inclusive Methodology for Comparison of Novel Diagnostic Tool Performance. [PDF]
Allen C +22 more
europepmc +1 more source

